Thrombosis and hemorrhage
著者
書誌事項
Thrombosis and hemorrhage
Lippincott Williams & Wilkins, c2003
3rd ed.
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Now in its Third Edition, this authoritative text continues to provide a comprehensive and systematic review of the biology, pathobiology, and clinical disorders of the hemostatic system. Its unique organization of the basic sciences coupled with clinical sections yields a user-friendly integrated text, and a reference tool that meets the needs of diverse investigators and clinicians of contemporary medicine for understanding the hemostatic system. New chapter topics covered in this edition include angiogenesis and vasculogenesis; hemorrhagic complications of antithrombotic therapy; interactions of coagulation and fibrinolytic proteins with the vessel wall; and less common thrombotic disorders.
目次
SECTION 1 COAGULATION AND FIBRINOLYSIS 1. Coagulation Cascade: An Overview 2. Molecular Genetics of Blood Coagulation 3. Regulation of Coagulation 4. Tissue Factor Pathway of Coagulation 5. Fibrin Formation and Stabilization 6. Fibrinolysis and its Regulation SECTION 2 PLATELETS 7. Regulation of Megakaryopoiesis 8. Platelet Morphology 9. Platelet Membranes and Receptors 10. Mechanisms of Platelet Activation and Signal Transduction SECTION 3 VESSEL WALL 11. Overview of the Endothelium 12. Angiogenesis and Vasculogenesis 13. Vascular Response to Injury 14. von Willebrand Factor 15. Interactions of Coagulation and Fibrinolytic Proteins with the Vessel Wall 16. Endothelium-derived Vasoactive Factors 17. Rheology SECTION 4 CLINICAL APPROACH TO BLEEDING AND THROMBOSIS 18. Approach to Bleeding 19. Approach to Thrombosis 20. Assessment of Arterial and Venous Thrombosis 21. Laboratory Methods in Hemostasis SECTION 5 QUANTITATIVE PLATELET DISORDERS 22. Thrombotic Microangiopathies 23. Alloimmune Thrombocytopenias 24. Drug-induced Thrombocytopenias 25. Immune Thrombocytopenic Purpura 26. Thrombocytosis SECTION 6 QUALITATIVE PLATELET DISORDERS 27. Congenial Disorders of Platelet Function 28. Acquired Disorders of Platelet Function SECTION 7 DISORDERS OF COAGULATION FACTORS AND FIBRINOLYSIS 29. von Willebrand Disease 30. Hemophilia-Factor VIII Deficiency 31. Other Coagulation Factor Deficiencies 32. Factor VIII and Other Coagulation Factor Inhibitors 33. Antiphospholipid Syndrome, Lupus, Anticoagulants, and Antiphospholipid Antibodies SECTION 8 THROMBOTIC DISORDERS 34. Relationship Between Thrombosis and Atherosclerosis 35. Inherited and Acquired Hypercoagulable States 36. Endotheliopathies SECTION 9 OTHER DISORDERS OF HEMOSTASIS 37. Less Common Thrombotic Disorders 38. Vascular Purpura and Diseases of Blood Vessels 39. Disseminated Intravascular Coagulation 40. Coagulopathy of Liver Failure and Vitamin K Deficiency 41. Maternal Hemostasis: Coagulation Problems of Pregnancy 42. Hemorrhage, Thrombosis, and Antithrombotic Therapy in Children 43. Interaction of Blood and Artificial Surfaces SECTION 10 MANAGEMENT OF BLEEDING 44. Platelet Transfusion Therapy 45. Plasma and Component Therapy 46. Non-transfusional Modalities SECTION 11 MANAGEMENT OF THROMBOSIS 47. Pharmacology of Antiplatelet Agents 48. Pharmacology of Heparin and Oral Anticoagulants 49. Pharmacology of Thrombolytic Agents 50. New Antithrombotic Strategies 51. Hemorrhagic Complications of Antithrombotic Therapy 52. Antithrombotic Interventions in Cerebrovascular Disease 53. Antithrombotic Therapy in Cardiovascular Disease 54. Antithrombotic Therapy in Peripheral Vascular Disease 55. Anticoagulants in Atrial Fibrillation 56. Prevention and Treatment of Venous Thromboembolic Disease 57. Gene Therapy of Thrombotic and Hemorrhagic Disorder
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