Biochemistry of signal transduction and regulation
著者
書誌事項
Biochemistry of signal transduction and regulation
Wiley-VCH, 2003
3rd, completely rev. ed
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注記
Previous ed.: 2001
Includes bibliographical references and index
内容説明・目次
内容説明
This all-new edition of a classic text has been thoroughly revised to keep pace with the rapid progress in signal transduction research. With didactic skill and clarity, the author relates the observed biological phenomena to the underlying biochemical processes. Directed at advanced students, teachers, and researchers in biochemistry and molecular biology, this book describes the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis. From the reviews of the previous edition: "Provides a comprehensive account of cell signaling and signal transduction and, where possible, explains these processes at the molecular level" - ("Angewandte Chemie"). "The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." - ("Biochemistry"). "This book is actually two books: "Regulation" and "Signal Transduction." ("Drug Research").
目次
Preface.1. The Regulation of Gene Expression.2. The Regulation of Enzyme Activity.3. Structure and Function of Signal Pathways.4. Signaling by Nuclear Receptors.5. G Protein-Coupled Signal Transmission Pathways.6. Intracellular Messenger Substances: Second Messengers.7. Ser/Thr-specific Protein Kinases and Protein Phosphatases.8. Signal Transmission via Transmembrane Receptors with Tyrosine-Specific Protein Kinase Activity.9. Signal Transmission via Ras Proteins.10. Intracellular Signal Transduction: The Protein Cascades of the MAP Kinase Pathways.11. Membrane Receptors with Associated Tyrosine Kinase Activity.12. Other Receptor Classes.13. Regulation of the Cell Cycle.14. Malfunction of Signaling Pathways and Tumorigenesis: Oncogenes and Tumor Suppressor Genes.15. Apoptosis.Index.
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