The laboratory mouse

著者

• Hedrich, Hans J.
• Bullock, Gillian R.

書誌事項

The laboratory mouse

edited by Hans J. Hedrich and Gillian Bullock

（The handbook of experimental animals）

Elsevier Academic Press, 2004

内容説明・目次

内容説明

Among animals used in research, teaching and testing, mice are now widely recognized as the most important model for human diseases and disorders. They comprise the majority of all experimental mammals and tend to be the model of choice used for research into many diseases/disorders including cancer, heart disease, asthma, Alzheimer's, Down syndrome, deafness, osteoporosis, obesity, diabetes and even mental health research. Additionally the laboratory mouse continues to play a widely publicized vital role in the human genome project.One of the most time-consuming activities in research laboratories is looking up information specific to the species or strain of animal being used. This book, part of the highly successful Handbook of Experimental Animals series, allows the user quick access to any point of interest on the mouse as an experimental model.

目次

History, Development and Genetics of the Mouse as a Laboratory Model Origin of the Laboratory Mouse and Related Historical Foundations Strain, Stock and Mutants Mouse Genomics Generation of Mouse Mutants by Sequence Information Driven and Random Mutagenesis The Mouse as an Animal Model for Human Diseases The Mouse in Preclinical Safety Studies Anatomy and Developmental Biology Gross Anatomy Normative Histology of Organs Imaging Introduction to Early Mouse Development Pathophysiology (including non-infectious diseases) Skin and Adnexes of the Laboratory Mouse Cardiovascular System Respiratory Tract Gastrointestinal System and Metabolism Inbred Mouse Models for Autoimmune Disease Hematology of the Mouse The Social Behaviour of Mice and its Sensory Control Neuroendocrine - Immune Network in Stress Circadian Rhythms of the Mouse Gerontology Diversity of Spontaneous Neoplasms in Commonly Used Inbred Strains and Stock of Laboratory Mice Infectious Agents and Diseases Viral Infections Animal Husbandry and Production Housing and Maintenance Gnotobiology and Breeding Techniques Assisted Reproduction and Cryopreservation Health Monitoring Nutrition of Laboratory Mice Procedures Legal Regulations for the Protection of Animals Used for Scientific Experiments Necropsy Methods Handling and Restraint Routes of Administration Collection of Body Fluids Anaesthesia, Analgesia and Euthanasia

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詳細情報

• NII書誌ID(NCID): BA69432276
• ISBN:
  • 9780123364258
• 出版国コード: ne
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Amsterdam
• ページ数/冊数: xvi, 600 p.
• 大きさ: 28 cm
• 親書誌ID:
  • BA48429342