Chemical biology : a practical course
Author(s)
Bibliographic Information
Chemical biology : a practical course
Wiley-VCH, c2004
Available at / 17 libraries
-
No Libraries matched.
- Remove all filters.
Note
Includes bibliographical references and index
Description and Table of Contents
Description
Take your first steps in combinatorial synthesis or synthesize bioactive molecules such as antibiotics. Search for mutations in DNA using chemical probes or perform a proteome analysis in yeast. The present selection of 12 inspiring experiments is tailored for maximum learning effect at minimal expense of time and equipment. Almost all currently used laboratory techniques in synthesis and analysis of bioactive compounds are represented at least once. Abundant practical hints are complemented by a thorough treatment of the underlying theory and mechanisms.
Table of Contents
Preface.Abbreviations.1. Introduction: Chemical Biology- A New Science at the Crossroads of Chemical and Biology (R. Breinbaur & H. Waldmann).2. DNA-Synthesis and DNA-Hybridization (S. Ficht, et al.). 3. Doubly Labeled Peptide Nucleic Acids (PNAs) as Probes for the Detection of DNA Point Mutations (O. Kohler, et al.). 4. Synthesis and Characterization of a Covalent Oligonucleotide-Streptavidin Conjugate and its Application in DNA-directed Immobilization (DDI) (F. Kukolka, et al.). 5. Solid Phase Synthesis of Peptides: Bradykinin Analogs and the Evaluation of Calcium Mobilization in PC-12 Cells (C. Katzka, et al.). 6. In silico Protein Ligand Design (M. A. Koch, et al.). 7. Lipidation of Proteins and Peptide: Farnesylation of the Ras Protein (S. Sommer, et al.). 8. Insertion of Lipidated Peptides into Model Membranes (D. Gottieb & A. Watzke).9. Isolation of Potato Phosphorylase and Enzymatic Synthesis of Amylose (M. Scheck, et al.). 10. Proteome Analysis: Identification of Proteins Isolated from Yeast (H. Prinz, et al.). 11. Lectins: Determination of the Sugar Specificity of Jacalin by a Sugar-Lectin Binding Assay (SLBA) (E. Gourzoulidou & S. Schlummer).12. Combinatorial Synthesis and Genetic Algorithm (T. Lessmann, et al.). 13. Solid Phase Synthesis of an Antibiotic (C. Peters, et al.). Appendix.Subject Index.
by "Nielsen BookData"
