Animal models of movement disorders
著者
書誌事項
Animal models of movement disorders
Elsevier/Academic Press, c2005
- : alk. paper
大学図書館所蔵 全6件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
HTTP:URL=http://www.loc.gov/catdir/description/els051/2004059730.html Information=Publisher description
内容説明・目次
内容説明
The use of animal models is a key aspect of scientific research in numerous fields of medicine. This book vigorously examines the important contributions and application of animal models to the understanding of human movement disorders and will serve as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. A vital feature of this book is an accompanying DVD with video clips of human movement disorders and their corresponding animal models. The book is divided into sections on Parkinson disease, Huntington disease, dystonia, tremor, paroxysmal movement disorders, ataxia, myoclonus, restless legs syndrome, drug-induced movement disorders, multiple system atrophy, progressive supranuclear palsy/corticobasal degeneration and spasticity. This book serves as an essential resource for both clinicians interested in the science being generated with animal models and basic scientists studying the pathogenesis of particular movement disorders.
目次
Table of Contents
Preface
List of Contributors
Section A: Scientific Foundations
A1: Classification and Clinical Features of Movement Disorders
A2: Animal Models and the Science of Movement Disorders
A3: Generation of Transgenic and Gene-Targeted Mouse Models of Movement Disorders
A4: Genetics of Spontaneous Mutations in Mice
A5: Assessment of Movement Disorders in Rodents
A6: Response Dynamics: Measurement of the Force and Rhythm of Motor Responses in Laboratory Animals
A7: Behavior in Drosophila: Analysis and Control
A8: Use of C. elegans to Model Human Movement Disorders
Section B: Parkinson Disease
B1: The Phenotypic Spectrum of Parkinson Disease
B2: MPTP-Induced Nigrostriatal Injury in Nonhuman Primates
B3: From Man to Mouse: The MPTP Model of Parkinson Disease
B4: Rotenone Rat and Other Neurotoxin Models of Parkinson Disease
B5: Drosophila Models of Parkinson Disease
B6: Phenotypical Characterization of Genetic Mouse Models of Parkinson Disease
B7: Utility of 6-Hydroxydopamine Lesioned Rats in the Preclinical Screening of Novel Treatments for Parkinson Disease
B8: Motor Complications in Primate Models of Parkinson Disease
B9: C. elegans Models of Parkinson Disease
Section C: Dystonia
C1: Clinical Features and Classification of the Human Dystonias
C2: The Genetically Dystonic Rat
C3: Animal Models of Benign Essential Blepharospasm and Hemifacial Spasm
C4: Mouse Models of Dystonia
C5: The Owl Monkey Model of Focal Dystonia
C6: DYT1 Transgenic Mouse
C7: The hph-1 Mouse
Section D: Huntington Disease
D1: Clinical and Pathological Characteristics of Huntington Disease
D2: Transgenic Rodent Models of Huntington Disease
D3: Knock-in and Knock-out Models of Huntington Disease
D4: Drosophila Models of Huntington Disease
Section E: Tremor Disorders
E1: Neurophysiologic Characterization of Tremor
E2: Essential Tremor
E3: Harmaline Tremor
E4: GABAA Receptor a1 Subunit Knockout Mice: A Novel Model of Essential Tremor
E5: Production and Physiological Study of Holmes Tremor in Monkeys
E6: The Campus Syndrome in Pietrain Pig
Section F: Myoclonus
F1: Pathophysiology, Neurophysiology, and Pharmacology of Human Myoclonus
F2: Post-Hypoxic Myoclonus in Rodents
F3: Baboon Model of Myoclonus
Section G: Tic Disorders
G1: Tourette Syndrome
G2: Animal Models of Tourette Syndrome
Section H: Paroxysmal Movement Disorders
H1: Paroxysmal Dyskinesias in Humans
H2: The Genetically Dystonic Hamster: An Animal Model of Paroxysmal Dystonia
H3: Mouse Models of Hyperekplexia
H4: Bovine Hyperekplexia
H5: Movement Disorders in Drosophila Mutants of Potassium Channels and Biogenic Amine Pathways
Section I: Progressive Supranuclear Palsy and Corticobasal Ganglionic Degeneration
I1: Progressive Supranuclear Palsy and Corticobasal Degeneration
I2: Genetic Susceptibility and Animal Modeling of PSP
I3: Rodent Models of Tauopathies
Section J: Multiple System Atrophy
J1: Clinical Spectrum and Pathological Features of Multiple System Atrophy
J2: Double-Lesion Animal Models of Multiple System Atrophy
J3: A Mouse Model for Multiple System Atrophy
Section K: Ataxias
K1: Clinical and Pathological Features of Hereditary Ataxias
K2: Acquired Ataxias
K3: Animal Models of Spinocerebellar Ataxia Type 1 (SCA1)
K4: Spinocerebellar Ataxia Type 2 (SCA2)
K5: SCA7 Mouse Models
K6: Animal Models of Friedreich Ataxia
K7: Animal Oculomotor Data Illuminate Cerebellum-Related Eye Movement Disorders
Section L: Spasticity
L1: Spasticity
L2: Hereditary Spastic Paraplegia: Clinical Features and Animal Models
L3: The Spastic Rat with Sacral Spinal Cord Injury
L4: Rat Spinal Cord Contusion Model of Spasticity
Section M: Drug-induced Movement Disorders
M1: Drug-Induced Movement Disorders
M2: Neuroleptic-Induced Acute Dystonia and Tardive Dyskinesia in Primates
M3: Motor Effects of Typical and Atypical Antipsychotic Drugs in Rodents
M4: Animal Models of Drug-Induced Akathisia
Section N: Restless legs Syndrome
N1: Clinical Features and Animal Models of Restless Legs Syndrome and Periodic Limb Movement
Index
「Nielsen BookData」 より