GTPases regulating membrane targeting and fusion

著者

• Balch, William Edward
• Der, Channing J.
• Hall, A. (Alan)

書誌事項

GTPases regulating membrane targeting and fusion

edited by William E. Balch, Channing J. Der, Alan Hall

（Methods in enzymology / editors in chief, Sidney P. Colowick, Nathan O. Kaplan, v. 403）

Elsevier Academic Press, c2005

注記

Includes bibliographical references and indexes

内容説明・目次

内容説明

Rab GTPases now comprise a family of >63 members. They are emerging as the key hub element controlling the membrane architecture of eukaryotic cells. They are intimately involved in vesicle targeting and fusion in both the endocytic and exocytic pathways and direct the assembly and disassembly of protein complexes that include regulators (GEFs and GAPs), effectors (tethers/motors) and fusion components (SNAREs) that control membrane targeting and fusion. During the last 3 years the field has virtually exploded with the identification and characterization of many new Rab proteins and their effectors. Our understanding of how Rab GTPases control membrane function remains at its infancy. This volume of Methods in Enzymology, GTPases Regulating Membrane Targeting and Fusion, provides a wealth of new concepts, approaches and tools to study Rab proteins in the test tube and in living cells that will be of strong benefit to both established laboratories and new investigators in the field to elucidate Rab GTPase function in cellular development, differentiation and proliferation.

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詳細情報

• NII書誌ID(NCID): BA74786686
• ISBN:
  • 0121828085
• 出版国コード: ne
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Amsterdam ; San Diego, Calif. ; Tokyo
• ページ数/冊数: xliii, 863 p., [28] p. of plates
• 大きさ: 24 cm
• 件名:
  • MESH : Enzymes
  • MESH : Membrane Fusion
• 親書誌ID:
  • BA00197543