Transient receptor potential (TRP) channels
著者
書誌事項
Transient receptor potential (TRP) channels
（Handbook of experimental pharmacology, v. 179）
Springer, c2007
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This volume provides up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field have written 35 essays which describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression.
目次
An Introduction on TRP Channels.- An Introduction on TRP Channels.- TRPC Channel Subfamily.- TRPC1 Ca2+-Permeable Channels in Animal Cells.- TRPC2: Molecular Biology and Functional Importance.- TRPC3: A Multifunctional, Pore-Forming Signalling Molecule.- Ionic Channels Formed by TRPC4.- Canonical Transient Receptor Potential 5.- TRPC6.- TRPC7.- TRPV Channel Subfamily.- Capsaicin Receptor: TRPV1 A Promiscuous TRP Channel.- 2-Aminoethoxydiphenyl Borate as a Common Activator of TRPV1, TRPV2, and TRPV3 Channels.- TRPV4.- TRPV5, the Gateway to Ca2+ Homeostasis.- TRPV6.- TRPM Channel Subfamily.- TRPM2.- TRPM3.- Insights into TRPM4 Function, Regulation and Physiological Role.- TRPM5 and Taste Transduction.- TRPM6: A Janus-Like Protein.- The Mg2+ and Mg2+-Nucleotide-Regulated Channel-Kinase TRPM7.- TRPM8.- Other TRP Channels.- TRPA1.- TRPP2 Channel Regulation.- TRP Proteins and Specific Cellular Functions.- Know Thy Neighbor: A Survey of Diseases and Complex Syndromes that Map to Chromosomal Regions Encoding TRP Channels.- TRP Channels of the Pancreatic Beta Cell.- TRP Channels in Platelet Function.- TRP Channels in Lymphocytes.- Link Between TRPV Channels and Mast Cell Function.- TRPV Channels' Role in Osmotransduction and Mechanotransduction.- Nociception and TRP Channels.- TRP Proteins - Integrators of Multiple Inputs.- Regulation of TRP Ion Channels by Phosphatidylinositol-4,5-Bisphosphate.- TRPC, cGMP-Dependent Protein Kinases and Cytosolic Ca2+.- Trafficking of TRP Channels: Determinants of Channel Function.- TRPC Channels: Interacting Proteins.- TRPC Channels: Integrators of Multiple Cellular Signals.- Phospholipase C-Coupled Receptors and Activation of TRPC Channels.- Erratum.- Erratum.
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