Principles of pharmacology : the pathophysiologic basis of drug therapy

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Principles of pharmacology : the pathophysiologic basis of drug therapy

[edited by] David E. Golan [et. al.]

Lippincott Williams & Wilkins, c2008

2nd ed

大学図書館所蔵 件 / 全41件

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This primary textbook for a first course in pharmacology offers an integrated, systems-based, and mechanism-based approach to understanding drug therapy. Each chapter focuses on a target organ system, begins with a clinical case, and incorporates cell biology, biochemistry, physiology, and pathophysiology to explain how and why different drug classes are effective for diseases in that organ system. Over 400 two-color illustrations show molecular, cellular, biochemical, and pathophysiologic processes underlying diseases and depict targets of drug therapy. Each Second Edition chapter includes a drug summary table presenting mechanism, clinical applications, adverse effects, contraindications, and therapeutic considerations. New chapters explain how drugs produce adverse effects and describe the life cycle of drug development. The fully searchable online text and an image bank are available on thePoint.

目次

FUNDAMENTAL PRINCIPLES OF PHARMACOLOGY Drug-Receptor Interactions Pharmacodynamics Pharmacokinetics Drug Metabolism Drug Toxicity PRINCIPLES OF NEUROPHARMACOLOGY Fundamental Principles of Neuropharmacology Principles of Cellular Excitability and Electrochemical Transmission Principles of Nervous System Physiology and Pharmacology Principles of Autonomic and Peripheral Nervous System Pharmacology Cholinergic Pharmacology Adrenergic Pharmacology Local Anesthetic Pharmacology Principles of Central Nervous System Pharmacology Pharmacology of GABAergic and Glutamatergic Neurotransmission Pharmacology of Dopaminergic Neurotransmission Pharmacology of Central Adrenergic and Serotonergic Neurotransmission Pharmacology of Abnormal Electrical Neurotransmission in the Central Nervous System General Anesthetic Pharmacology Pharmacology of Analgesia Pharmacology of Drug and Alcohol Abuse and Dependence PRINCIPLES OF CARDIOVASCULAR PHARMACOLOGY Pharmacology of Cardiac Rhythm Pharmacology of Cardiac Contractility Pharmacology of Volume Regulation Pharmacology of Vascular Tone Pharmacology of Hemostasis and Thrombosis Pharmacology of Cholesterol and Lipoprotein Metabolism Integrative Cardiovascular Pharmacology: Hypertension, Ischemic Heart Disease, and Heart Failure PRINCIPLES OF ENDOCRINE PHARMACOLOGY Pharmacology of the Hypothalamus and Pituitary Gland Pharmacology of the Thyroid Gland Pharmacology of the Adrenal Cortex Pharmacology of Reproduction Pharmacology of the Endocrine Pancreas Pharmacology of Bone Mineral Homeostasis PRINCIPLES OF CHEMOTHERAPY Principles of Antimicrobial and Antineoplastic Pharmacology Pharmacology of Bacterial Infections: Central Dogma Processes Pharmacology of Bacterial Infections: Cell Wall Synthesis Pharmacology of Fungal Infections Pharmacology of Parasitic Infections Pharmacology of Viral Infections Pharmacology of Cancer: DNA Synthesis, Stability, and Maintenance Pharmacology of Cancer: Signal Transduction Principles of Combination Chemotherapy PRINCIPLES OF INFLAMMATION AND IMMUNE PHARMACOLOGY Principles of Inflammation and the Immune System Pharmacology of Eicosanoids Histamine Pharmacology Pharmacology of Hematopoietic and Immune Cell Stimulation Pharmacology of Immunosuppression Integrative Inflammation Pharmacology: Peptic Ulcer Disease Integrative Inflammation Pharmacology: Asthma Integrative Inflammation Pharmacology: Gout FUNDAMENTALS OF DRUG DEVELOPMENT AND REGULATION Drug Discovery and Preclinical Development Clinical Drug Evaluation and Regulatory Approval Detection and Management of Adverse Events in Marketed Drugs POISONING BY DRUGS AND ENVIRONMENTAL TOXINS FRONTIERS IN PHARMACOLOGY Pharmacogenomics Protein-Based and Gene Therapies Drug Delivery Modalities

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