CiNii 図書 - Seafood and freshwater toxins : pharmacology, physiology, and detection

The occurrence of marine and freshwater toxins is a rapidly evolving problem due to ever-changing circumstances. Expanding international commerce is forcing cargo ships into virgin territory, deforestation and pollution violate the natural ecological balance, and a changing climate holds unknown potential to alter current factors and trigger toxic blooms in new forms, at new rates, and in new places. Fortunately, with notable advances in analysis technology, the body of knowledge in the field is equally dynamic. In just six years since the first edition, toxins that warranted only line listings, including pfiestra, gambierol, and polycavernoside, are now worthy of entire chapters, requiring a new edition to encompass the expanding scope of the field. Emphasizes Human Response to New Toxins Gathering contributions from international experts, Seafood and Freshwater Toxins: Pharmacology, Physiology, and Detection, Second Edition provides an overview of the current state-of-knowledge from several perspectives. Incorporating toxicology, chemistry, ecology, and economics, the book covers the biological aspects of the bloom and the effects and actions of each toxin with emphasis on human response. This edition includes more information on detection and analysis, toxicological information on previously little known toxins, and food safety issues. Incorporating Pharmacological, Legal, and Economic Aspects, this book- Begins with general information on risk assessment and analytical techniques Cover several categories of toxins by function and biomechanism Considers potential pharmacological applications and the use of toxins as precursors to therapeutic drugs Highlights the legal and economic perspectives of toxic incidence in industrial activity and international regulation and monitoring programs Describes new toxins by their individual chemical structure, ecobiology, metabolism, detection methods, determination, pharmacology, and toxicology

General Considerations Risk Assessment of Marine Toxins, T. Aune Analysis of Marine Toxins - Techniques, Method Validation, Calibration Standards and Screening Methods, P. Holland The Epidemiological Impact of Toxic Episodes Diarrheic Toxins, J. Gestal Neurotoxic Toxins, B. Gessner and J.B. McLaughlin Diversity of Marine Toxins as Pharmacological Tools Calcium Channels for Exocytosis: Functional Modulation with Toxins, A. Garcia The Mouse Bioassay as a Universal Detector, L.M Botana Paralytic Shellfish Poisoning (PSP) Metabolism of Paralytic Shellfish Toxins Incorporated into Bivalve, M. Kodama Chemical Analysis, B. Ben and A. Villar Pharmacology and Toxicology: Biological Detection Methods, B. Suarez Diarrheic Episodes: Phosphatase Inhibitors. Chemistry, Metabolism, Chemical Analysis of OA Group Toxins, P. MacNabb Pharmacology and Toxicology, A. Tubaro Lipophyllic Toxins: Non-phosphatase Inhibitors Planktonic Dinoflagellates which Produce Polyether Toxins of the Old "DSP Complex", B. Reguera Yessotoxins Chemistry, Metabolism, Chemical Analysis, E. Fatorusso and P. Ciminello Pharmacology and Mechanism of Action: Biological Detection, A. Alfonso Toxicology of the Yessotoxins, R. Munday Pectenotoxins Chemistry, Metabolism, and Chemical Detection Methods of Pectenotoxins, T. Suzuki Pharmacology of Pectenotoxins, N. Vilarino Toxicology of Pectenotoxins, R. Munday Domoic Acid Intoxication Ecobiology of ASP Producing Diatoms, Y. Kotaki Domoic Acid: Detection Methods, Pharmacology and Toxicology, A. Tasker Non-PSP Neurotoxic Episodes The Ecobiology of the Brevetoxin, Ciguatoxin and Cyclic Imine Producers, L. Mackenzie Ciguatera Toxins Ciguatera Toxins: Chemistry, Toxicology and Detection, R. Dickey Maitotoxin Maitotoxin: a Unique Pharmacological T ool for Elucidating Ca2+-Dependent Mechanisms, A. Darszon Brevetoxins The Molecular and Integrative Basis to Brevetoxin Toxicity, J. Ramsdell Dection of Brevetoxins in the 21st Century, M. Poli Cyclic Imines and Spirolides Cyclic Imine Toxins: Chemistry, Biogeography, Biosynthesis and Pharmacology, A. Cembella Toxicology of Cyclic Imines: Gymnodimine, Spirolides, Pinnatoxins, Pteriatoxins, Prorocentrolide, Spiro-Prorpcentrimine, and Symbiomines, R. Munday Polycavernosides: Gambierol Polycavernosides: Gambierol, Chemistry, Pharmacology, Toxicology, and Detection, C. Louzao Palytoxin, Ostreocin, Ovatatoxin Palytoxin and Analogues: Ecobiology and Origin. Chemistry, Metabolism and Chemical Analisis, P. Katikou Diverse Chemical Structures and Bioactivities of Marine Toxin: Palytoxin and Symbiodinolide, D.Uemura Palytoxins: Pharmacology and Biological Detection Methods, C. Vale Occurrence and Toxicology of Palytoxins, R. Munday Pfiesteria Toxins Pfiesteria spp. Toxins: Unresolved Questions and an Alternative Hypotheses, G. Vasta and A. Place Azaspiracids Pharmacology and Epidemiological Impact of Azaspiracids, M. Ryan Azaspiracids: Chemistry, Bioconversion and Determination, K. James Toxicology of Azaspiracid 1, E. Ito Cyanobacterial Toxins Cyanobacterial Toxins in Aquaculture, P.T Smith Neurotoxins Cyanobacterial Neurotoxins, Anatoxin-a and Analogues: Detection and Analysis, K. James Hepatotoxins Cyanobacterial Hepatotoxins: Chemistry, Biosynthesis, and Occurrence, M. Welker Hepatotoxins: Context and Chemical Determination, K. James Toxins as a Starting Point to Drugs Marine Neurotoxins as a Starting Point to Drugs, M.R. Waters Legal and Economical Views Incidence of Marine Toxins on Industrial Activity, J M Vieites Toxin Monitoring Programs and Regulatory View, M.L. Rodriguez-Velasco

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Seafood and freshwater toxins : pharmacology, physiology, and detection

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