Angiogenesis : in vivo systems

Author(s)

• Cheresh, David A.

Bibliographic Information

Angiogenesis : in vivo systems

edited by David A. Cheresh

（Methods in enzymology / editors in chief, Sidney P. Colowick, Nathan O. Kaplan, v. 444-445）

Academic Press, c2008

• pt. A
• pt. B

Note

Includes bibliographical references and indexes

Description and Table of Contents

Volume

pt. A ISBN 9780123743138

Description

Angiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance of angiogenesis modulators. In many serious disease states, however, the body loses control over angiogenesis. Diseases that are angiogenesis-dependent result when blood vessels either grow excessively or insufficiently. Understanding how angiogenesis "works" and how to control it, will have massive implications on the management, treatments, and ultimately the prevention of many common (and not so common) diseases. Angiogenesis cuts across virtually every discipline. The Angiogenesis Foundation identified angiogenesis as a "common denominator" in our most serious diseases. Excessive angiogenesis occurs in diseases such as cancer, diabetic blindness, age-related macular degeneration, rheumatoid arthritis, psoriasis, and many other conditions. Insufficient angiogenesis occurs in diseases such as coronary artery disease, stroke, and delayed wound healing.

Table of Contents

• Isolation of natural angiogenesis inhibitors and their function
• Chick CAM models
• Ultrastructure analysis of blood vessels
• Zebrafish models
• Lymphangiogenesis models and applications
• Models of vascular permeability
• Tumor models to study angiogenesis inhibitors
• Studying hemangiomas and vascular malformations
• Ocular models of angiogenesis
• Models of ischemia and ischemia/reperfusion
• Vascular neural patterns
• Identification of important genes in vascular development
• Imaging of tumor blood vessels
• Imaging of blood vessels (in situ terminal models)
• In vivo assays to screen anti-angiogenic agents
• Blood vessel normalization
• Patterning (neurons, ECM, EC) during angiogenesis, vascular regression, inhibitors

Volume

pt. B ISBN 9780123743145

Description

Understanding how angiogenesis "works" and how to control it will have massive implications on the management, treatments, and ultimately the prevention of many common (and not so common) diseases. Angiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance of angiogenesis modulators. In many serious disease states, however, the body loses control over angiogenesis. Diseases that are angiogenesis-dependent result when blood vessels either grow excessively or insufficiently.

Table of Contents

Inflammation and (lymph)angiogenesis Color-Coded Fluorescent Mouse Models of Cancer Cell Interactions with Blood Vessels and Lymphatics Bone-Marrow Derived Vascular Progenitors and Proangiogenic Monocytes in Tumors SCREENING PHAGE DISPLAY PEPTIDE LIBRARIES FOR VASCULAR TARGETED PEPTIDES Avian embryos: a model for the study of primary vascular assembly in warm-blooded animals Anti-cancer effects of VEGF inhibitors: insights from mouse models MOLECULAR IMAGING OF TUMOR VASCULATURE Proteomic mapping of the vascular endothelium as it exists in vivo for vascular targeting Development of Coronary Vessels Methods for evaluating uroplacental angiogenesis and their application using animal models Intravital Microscopic Investigation of Leukocyte Interactions with the Blood Vessel Wall Placental remodeling of the uterine vasculature An in vivo experimental model for postnatal vasculogenesis Assessment of arteriogenesis Methods to Study Myeloid Cell Roles in Angiogenesis

by "Nielsen BookData"

Details

• NCID: BA8765893X
• ISBN:
  • 9780123743138
  • 9780123743145
• Country Code: ne
• Title Language Code: eng
• Text Language Code: eng
• Place of Publication: Amsterdam ; Tokyo
• Pages/Volumes: 2 v.
• Size: 24 cm
• Parent Bibliography ID:
  • BA00197543