Physical biology of the cell
著者
書誌事項
Physical biology of the cell
Garland Science, c2009
- : pbk
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注記
"With problems, solutions, and editorial assitance of Herman G. Garcia"
Includes bibliographical references and index
内容説明・目次
内容説明
Physical Biology of the Cell is a biophysics textbook that explores how the basic tools and insights of physics and mathematics can illuminate the study of molecular and cell biology. Drawing on key examples and seminal experiments from cell biology, the book demonstrates how quantitative models can help refine our understanding of existing biological data and also be used to make useful predictions. The book blends traditional models in cell biology with the quantitative approach typical in physics, in order to introduce the reader to both the possibilities and boundaries of the emerging field of physical biology. While teaching physical model building in cell biology through a practical, case-study approach, the text explores how quantitative modeling can be used to build a more profound, intuitive understanding of cell biology.
目次
Part I The Facts of Life
1. Why: Biology By the Numbers
2. What and Where: Construction Plans for Cells and Organisms
3. When: Stopwatches at Many Scales
4. Who: "Bless the Little Beasties"
Part II Life at Rest
5. Mechanical and Chemical Equilibrium in the Living Cell
6. Entropy Rules!
7. Two-State Systems: From Ion Channels to Cooperative Binding
8. Random Walks and the Structure of Macromolecules
9. Electrostatics for Salty Solutions
10. Beam Theory: Architecture for Cells and Skeletons
11. Biological Membranes: Life in Two Dimensions
Part III Life in Motion
12. The Mathematics of Water
13. A Statistical View of Biological Dynamics
14. Life in Crowded and Disordered Environments
15. Rate Equations and Dynamics in the Cell
16. Dynamics of Molecular Motors
17. Biological Electricity and the Hodgkin-Huxley Model
Part IV The Meaning of Life
18. Sequences, Specificity and Evolution
19. Network Organization in Space and Time
20. Whither Physical Biology
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