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v. 78 ISBN 9780123748270
内容説明
Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. This eclectic volume features articles on a variety of topical subjects.
目次
1. Angiopoietins and Tie Receptors (Nikolov)
2. Tandem repeats in proteins: sequence, structure and function (Kajava)
3. Protein aggregation: from inclusion bodies to amyloid and biomaterials (Mitraki)
4. Modeling and structural determination and design (Morozov)
5. Structure and role of periplasmic chaperones involved in bacterial secretion (Waksman)
6. Structural bases for corneal transparency (Knupp)
7. Taking charge of proteins: the simple side of intermolecular electrostatics and protein aggregation (Faull)
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v. 80 ISBN 9780123812643
内容説明
Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome.
While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale.
目次
Proteomics technologies for the global identification and quantification of proteins
Ian A. Brewis and P. Brennan
Targeted metabolomics and mass spectrometry
E. Dudley, M. Yousef, Y. Wang, W.J. Griffiths
Mechanisms of Protein Circular Dichroism: Insights from Computational Modelling
Tatyana Karabencheva and Christo Christov
Fine architecture and mutation mapping of human brain inhibitory system ligand gated ion channels by high-throughput homology modeling
Jonathan G. L. Mullins, Seo-Kyung Chung and Mark I. Rees
Positive and Negative Modulation of Nicotinic Receptors
Hugo R. Arias
Sonochemically Born Proteinaceous Micro- and Nanocapsules
Elena D. Vassileva and Neli S. Koseva
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v. 79 ISBN 9780123812780
内容説明
Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome.
While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale.
目次
1. Genomic studies and computational predictions of nucleosome positions and formation energiesAlexandre V. Morozov and Denis Tolkunov 2. Protein Homorepeats : Sequences, Structures, Evolution and FunctionsAndrey V. Kajava and Julien Jorda3. Protein Aggregation: from Inclusion Bodies to Amyloid and Biomaterials Anna Mitraki4. Taking charge of proteins: from neurodegeneration to industrial biotechnology Bryan F. Shaw , Demetri T. Moustakas , Julian P. Whitelegge , and Kym F. Faull 5. Histone Acetylation, Acetyltransferases, and Ataxia - Alteration of Histone Acetylation and Chromatin Dynamics is Implicated in the Pathogenesis of Polyglutamine Expansion Disorders Jean-Pol Vigneron and Priscilla SimonisShaun D. McCullough and Patrick Gran
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v. 84 ISBN 9780123864833
内容説明
Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. This volume features articles on Protein Aggregation.
目次
1. Effects of Metal Ions and Nucleic Acids on Protein Aggregation
Changlin Liu
2. Lysozyme aggregation
R Swaminathan
3. Protein aggregation in a membrane environment
Galyna Gorbenko
4. Physical Chemical aspect of amyloidine peptides aggregation
Jordan Petkov
5. Serpin polymerisation and aggregation
Stephen Bottomley
6. Practical considerations of aggregation in protein pharmaceuticals
Bilikallahalli Muralidhara
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v. 94 ISBN 9780128001684
内容説明
This eclectic volume features two major topics: applications of mass spectrometry in bioscience; and computational methods for analysis of protein structure and interactions with other macromolecules.
Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics.
目次
Bioinformatics Tools to Identify and Quantify Proteins using Mass Spectrometry Data
Soyoung Ryu
Unraveling Oxidation-Induced Modifications in Proteins by Proteomics
Carolina Panis
Role of Proteomics in Biomarker Discovery: Prognosis and Diagnosis of Neuropsychiatric Disorders
Suman Patel
On the use of Knowledge-Based Potentials for the Evaluation of Models of Protein-Protein, Protein-DNA and Protein-RNA Interactions
Oriol Fornes, Javier Garcia-Garcia, Jaume Bonet and Baldo Oliva
Algorithms, Applications and Challenges of Protein Structure Alignment
Jianzhu Ma and Sheng Wang
Application of Evolutionary based in silico Methods to Predict the Impact of Single Amino Acid Substitutions in Vitelliform Macular Dystrophy
C. George Priya Doss, Chiranjib Chakraborty, N. Monford Paul Abishek, D. Thirumal Kumar and Vaishnavi Narayanan
Current State of the Art Molecular Dynamics Methods and Applications
Dimitrios Vlachakis, Elena Bencurova, Nikitas Papangelopoulos and Sophia Kossida
Intrinsically Disordered Proteins - Relation to General Model Expressing the Active Role of the Water Environment
Barbara Kalinowska, Mateusz Banach, Leszek Konieczny, Damian Marchewka and Irena Roterman
Conformational Elasticity can Facilitate TALE-DNA Recognition
Hongxing Lei, Jiya Sun, Enoch P. Baldwin, David J. Segal and Yong Duan
Computational Approaches and Resources in Single Amino Acid Substitutions Analysis towards Clinical Research C. George Priya Doss, Chiranjib Chakraborty, Vaishnavi Narayan and D. Thirumal Kumar
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v. 101 ISBN 9780128033678
内容説明
The Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.
目次
The Eukaryotic Translation Initiation Factor 4E (eIF4E) as a Therapeutic Target for Cancer
Sara Karaki, Claudia Andrieu, Hajer Ziouziou and Palma Rocchi
Anti-Tumor Lipids - Structure, Functions and Medical Applications
Aneliya Kostadinova, Tanya Topouzova-Hristova, Albena Momchilova, Rumiana Tzoneva and Martin R. Berger
Telomere Repeat Factor 2 (Trf2) is Responsible for the Telomere Attachment to the Nuclear Membrane
Nadya V. Ilicheva, Olga I. Podgornaya and Alex P. Voronin
Alterations in Gene Expression in Depression - Prospects for Personalize Patient Treatment
Rossen Donev and Khaled Alawam
Evolution and Coevolution of Prc2 Genes in Vertebrates and Mammals
Xi Liu, Jingwen Yang, Nan Wu, Ruixian Song and Hao Zhu
Quartz-Crystal Microbalance (QCM) for Public Health: An Overview of its Applications
Nicola Luigi Bragazzi, Daniela Amicizia, Donatella Panatto, Daniela Tramalloni, Ivana Valle and Roberto Gasparini
Porous Alumina as a Promising Biomaterial for Public Health
Nicola Luigi Bragazzi, Roberto Gasparini, Daniela Amicizia, Donatella Panatto and Claudio Larosa
Human Papillomavirus (HPV) Vaccine: State of the Art and Future Perspectives
Donatella Panatto, Daniela Amicizia, Nicola Luigi Bragazzi, Emanuela Rizzitelli, Daniela Tramalloni, Ivana Valle and Roberto Gasparini
SHOPIN: Semantic Homogeneity Optimization in Protein Interaction Networks
Kire Trivodaliev, Slobodan Kalajdziski, Ilinka Ivanoska, Biljana Risteska Stojkoska and Ljupco Kocarev
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