Protein interactions as targets in drug discovery
著者
書誌事項
Protein interactions as targets in drug discovery
（Advances in protein chemistry and structural biology, v. 121）
Academic Press, an imprint of Elsevier, 2020
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注記
Includes bibliographical references
内容説明・目次
内容説明
Protein Interactions as Targets in Drug Discovery, Volume 121, is dedicated to the design of therapeutics, both experimental and computational, that target protein interactions. Chapters in this new release include Trends in structure based drug design with protein targets, From fragment- to peptide-protein interaction: addressing the structural basis of binding using Supervised Molecular Dynamics (SuMD), Protein-protein and protein-ligand interactions: identification of potential inhibitors through computational analysis, Aromatic-aromatic interactions in protein-drug and protein-protein interactions, Role of protein-protein interaction in allosteric drug design within the human methyltransferome, and much more.
目次
1. Latest trends in structure based drug design with protein targets Angshuman Bagchi 2. From fragment- to peptide-protein interaction: addressing the structural basis of binding using Supervised Molecular Dynamics (SuMD) Stefano Moro 3. Protein-protein and protein-ligand interactions: identification of potential inhibitors through computational analysis M. Michael Gromiha 4. Aromatic-aromatic interactions in protein-drug and protein-protein interactions Adrian Gustavo Turjanski 5. Role of protein-protein interaction in allosteric drug design within the human methyltransferome Guang Hu 6. Protein-Protein Interactions as the Basis for Cyclin-Dependent Kinase Inhibition Mark Klein 7. Targeting FOXP3 complex ensemble in drug discovery Bin Li 8. Targeting arrestin interactions with its partners for therapeutic purposes Vsevolod V. Gurevich 9. Protein interactomics in kidney stone research Visith Thongboonkerd 10. Human oral microbiome protein-protein interaction: a cross-talk with health systemic implications Marlene M.T. Barros 11. Protein-protein complexes as targets for drug discovery against infectious diseases Yusuf Akhter 12. Therapeutic intervention of protein-protein interactions in innate immunity Kevin J. Lumb 13. Physicochemical determinants of antibody-protein interactions Sibel Kalyoncu Uzunlar
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