Insulin resistance : childhood precursors and adult disease
著者
書誌事項
Insulin resistance : childhood precursors and adult disease
（Contemporary endocrinology）
Humana Press, c2008
- hbk
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内容説明・目次
内容説明
In the mid 1990s, Drs. Gerald Reaven identified a constellation of clinical findings, known variously as the metabolic syndrome, syndrome X, insulin resistance s- drome or insulin resistance-related disorders, that are associated with an increased risk of heart disease and diabetes. Interest in this topic grew rapidly, culminating in the publication by this series of the book, Insulin Resistance and the Metabolic Syndrome X, edited by Drs. Reaven and Laws in 1999. Since the original publication of that now classic volume, the world's population has continued to become more obese and sedentary and the prevalence of disorders related to insulin resistance has continued to increase throughout the developed and developing world. Of great concern in the last decade is the extension of these deleterious lifestyle patterns to the pediatric population, leading to both obesity and the appearance of insulin resistance-related disorders in youth as well as adults. Today, about one in three children and adolescents in the United States is overweight or obese, and this prevalence approaches one in two among adolescents in certain minority groups. In addition, components of this cardiovascular risk constellation are now being recognized in young adults, adolescents, and even children. Youth are increasingly developing type 2 diabetes, fatty liver disease, hypertriglyceridemia, hypertension, polycystic ovarian syndrome, sleep apnea, orthopedic and psychiatric complications, as well as other complications of obesity and insulin resistance.
目次
Epidemiology
The metabolic syndrome: definitions, controversies, and clinical utility. Lewis W Johnson MD, Ruth S Weinstock MD, PhD
Epidemiology of the Metabolic syndrome and related disorders in children and adolescents - Jennifer L Foltz MD, Stephen R Cook MD, MPH
Metabolic syndrome in children and adolescents worldwide - Orit Pinhas-Hamiel MD
Maternal-fetal contributors to the insulin resistance syndrome in youth - Dana Dabelea MD, PhD
Early childhood contributions to insulin resistance - David B Dunger MD, FRCP, FRCPCH, Burak Salgin, Ken K Ong MRCPCH PhD
Pathophysiology
Molecular Mechanisms of insulin resistance - Boris Draznin MD, PhD
Techniques used to assess insulin action - Michael J Pagliassotti PhD, Kyle T. Pfaffenbach MS, Tracy J. Horton
Adiposity is the enemy: body composition and insulin sensitivity - J Higgins PhD, William T Donahoo MD
Ectopic fat deposition: adiponectin and insulin resistance in obese adolescents - Anna MG Cali MD, Sonia Caprio MD
Mediators of insulin resistance - Rocio Periera MD, David Maahs MD
Insulin resistance and the pathogenesis of cardiovascular disease. - Ramzi Ajjan MRCP, MMed.Sci, PhD, Mark T Kearn FRCP, PhD, Peter T Grant FRCP, MD
Insulin Resistance and Cardiovascular disease: Cecilia C Low Wang MD
The liver and insulin resistance: the important convergence of endocrinology and hepatology - Charissa Y Chang, MD , Kerry Whitt MD, Zhenqi Liu MD, Stephen H Caldwell MD
Polycystic Ovarian Syndrome and metabolic syndrome: Marie-Helene. Pesant MD, Jean-Patrice BaillargeonMD
Treatment
Effects of Exercise in Metabolic Syndrome and Diabetes: A Central Role for Insulin Sensitivity - Irene E Schauer MD, PhD, Judith.G. Regensteiner PhD, Jane EB. Reusch MD
Weight loss medications and the metabolic syndrome - Linda Buckley MD, Daniel Bessessen MD.
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