AB metabolism and alzheimer's disease
著者
書誌事項
AB metabolism and alzheimer's disease
（Neuroscience intelligence unit）
Landes Bioscience/Eurekah.com, c2003
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注記
Includes bibliographies and index
内容説明・目次
内容説明
This book provides information regarding three major aspects of A metabolism: generation from its precursor, degradation within the brain, and transport out of the brain. It is useful for graduate students, post-doctoral fellows, and scientists both in this and other disciplines.
目次
1. Overview-Ass Metabolism: From Alzheimer Research to Brain Aging C o n tro 2. ss-Secretase: Progress and Open Questions 3. APP a-Secretase, a Novel Target for Alzheimer Drug Therapy 4. ?-Secretase and Presenilin 5. Functional Roles of APP Secretases 6. Proteolytic Degradation of Ass by Neprilysin and Other Peptidase 7. Ass Degradation by Endothelin-Converting Enzymes 8. Ass Metabolism in Cholesterol Enriched Membrane Microdomains 9. Amyloid ss-Protein in Low-Density Membrane Domains 10. Transport-Clearance Hypothesis for Alzheimer's Disease and Potential Therapeutic Im plication 11. Potential Role of Endogenous and Exogenous Ass Binding Molecules in Ass Clearance and M etabolism 12. Modulating Amyloid-ss Levels by Immunotherapy: A Potential Therapeutic Strategy for the Prevention and Treatm ent of Alzheimer's Disease
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