The impact of tumor biology on cancer treatment and multidisciplinary strategies
著者
書誌事項
The impact of tumor biology on cancer treatment and multidisciplinary strategies
(Medical radiology : diagnostic imaging and radiation oncology, . Radiation oncology)
Springer, c2009
大学図書館所蔵 全4件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Te rapidly changing concepts in radiation oncology with the development of more precise - strumentation for delivery of radiation therapy and a greater emphasis on hypofractionation technologies require a very intimate knowledge of tumor biology and the infuence of various biologic factors on dose distribution within the tumor in terms of homogeneity as well as prev- tion of any late efects on normal tissue surrounding the tumor itself. Not only are these major factors in clinical practice but also the known factors of inhomogeneity of cancer cells, the impact of microenvironment in terms of radiation efect, and host factors make it mandatory to design therapeutic strategies to improve the outcome and to diminish any potential short-term or lo- term risks from the radiation therapy. Te authors have developed an outstanding text that deals with these strategies and how they would impact on established and emerging new technologies and treatment. Te context of the presentations within a multidisciplinary combined modality therapy program is incredibly - portant. In this volume, various topics are reviewed including tumor genesis, cell proliferation, - giogenesis, the physiologic characteristics of malignant tissues, invasion and adhesion, the route and role pursued in the development of metastasis, and the role of the human immune system in cancer prevention and development.
目次
Tumorigenesis.- Tumor Growth and Cell Proliferation.- Angiogenesis.- Tumor Physiology (Phenomenology).- Adhesion, Invasion, Integrins and Beyond.- Development of Metastases.- Role of the Immune System in Cancer Development and Therapeutic Implications.- Cancer Prevention .- Tumor Detection by Morphological and Biological Imaging.- Tumor Detection by Biological Markers (Serum, Urine, Breathing Gas, Proteomics).- Quantitative Cell Kill by Chemo- and Radiotherapy.- Impact of Molecularly Targeted Agents on Cell Kill in Bi- or Trimodal Approaches (i.e. plus Chemo, Radio-, or Radiochemotherapy).- Translational Studies for Target-Based Drugs.- Molecular Mechanisms of Treatment Resistance.- Physiological Mechanisms of Treatment Resistance.- Influence of Repopulation on Treatment Resistance.- Molecular Tools, Gene Expression Profiling.- Strategies of Gene Transfer/Silencing and Technical Considerations.- Tumor Biology's Impact on Clinical Cure Rates.- Can Dose-Escalated Radiotherapy Eventually Cure All Biologically Distinct Subsets of a Certain Tumor Type? Answers from Stereotactic Lung and Liver Radiotherapy Experience.-Low-Dose Radiotherapy - A Chemopotentiator?.- Treatment of the Primary Tumor in Metastatic Cancer: Influence on Outcome.- Subject Index.- List of Contributors.
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