Bone and osteoarthritis
著者
書誌事項
Bone and osteoarthritis
（Topics in bone biology, v. 4）
Springer-Verlag, c2007
- hbk
- hbk
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The molecular and cellular approaches to the relationship of joint and bone problems distinguish this from other books on the topic. Advances in bone and joint biology enable practitioners to approach clinical problems more comprehensively. Emphasis on genetics and on newer viewpoints and approaches, exemplified by the possible effect of subchondral bone on osteoarthritis, gives a wider viewpoint to the reader and may enable novel approaches to solving a clinical problem.
目次
The Pathogenesis of Osteoarthritis.- The Role of Bone in the Development of Osteoarthritis.- Cytokines, Growth Factors, and Bone-Derived Factors in Cartilage.- The Synovium and Its Role in Osteoarthritis.- Cartilage Matrix Destruction.- Anabolic Mediators of Cartilage Healing.- Chondrocyte Hypertrophy and Apoptosis at the Cartilage-Bone Interface.- Genetic and Epigenetic Aspects of Osteoarthritis.- Animal Models.- Biomechanical Aspects: Joint Injury and Osteoarthritis.- Novel Osteoarthritis Therapeutics.
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