NF-κB in health and disease
著者
書誌事項
NF-κB in health and disease
（Current topics in microbiology and immunology, 349）
Springer Berlin, c2011
- タイトル別名
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NF-kB in health and disease
大学図書館所蔵 全7件
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology-from immunity and inflammation to apoptosis, cell survival, growth, and proliferation
目次
Preface.- Understanding the Logic of I B:NF- B Regulation in Structural Terms.- NF- B/Rel proteins and the humoral immune responses of Drosophila melanogaster.- Specialized chromatin patterns in the control of inflammatory gene expression.- IKK regulation and human genetics.- Control of NF- B activity by proteolysis.- NF- B and Innate Immunity.- NF- B and mucosal homeostasis.- IKK and NF- B mediated functions in carcinogenesis.- Macrophages and NF- B in Cancer.- NF-kappaB in liver cancer - the plot thickens.- NF-kappaB as a target for oncogenic viruses.- Inhibition of NF- B signaling as a strategy in disease therapy.- Subject index
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