Gene transfer vectors for clinical application

Author(s)

• Friedmann, Theodore

Bibliographic Information

Gene transfer vectors for clinical application

edited by Theodore Friedmann

（Methods in enzymology / editors in chief, Sidney P. Colowick, Nathan O. Kaplan, 507）

Academic/Elsevier, c2012

• hbk.

Note

Includes indexes

Description and Table of Contents

Description

This volume of Methods in Enzymology looks at Gene Transfer Vectors for Clinical Application. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume covers such topics as General principles of retrovirus vector design, Chronic granulomatous disease (CGD), Gene therapy for blindness, and Retrovirus genetic strategy and vector design.

Table of Contents

Preface: The successful clinical use of viral vectors for human gene therapy. General principles of retrovirus vector design Strategies for retrovirus-based correction of severe, combined immunodeficiency (SCID) Retrovirus and lentivirus vector design and methods of cell conditioning Analysis of the clonal repertoire of gene corrected cells in gene therapy Developing novel lentiviral vectors into clinical products Lentivirus vectors in beta-thalassemia Gene Therapy for Chronic Granulomatous Disease Alternative splicing caused by lentiviral integration in the human genome Genotoxicity assay for gene therapy vectors in tumor prone Cdkn2a-/- mice Lentiviral Hematopoietic Cell Gene Therapy for X-linked Adrenoleukodystrophy Retroviral replicating vectors in cancer Adeno-associated virus vectorology, manufacturing and clinical applications Gene Delivery To The Retina: From Mouse To Man Generation of hairpin-based RNAi vectors for biological and therapeutic application Recombinant adeno-associated viral vector reference standards NIH oversight of human gene transfer research involving retroviral, lentiviral and adeno-associated virus vectors and the role of the NIH recombinant DNA advisory committee draft Regulatory structures for gene therapy medicinal products in the European Union

by "Nielsen BookData"

Details

• NCID: BB08878235
• ISBN:
  • 9780123865090
• Country Code: ne
• Title Language Code: eng
• Text Language Code: eng
• Place of Publication: Amsterdam ; Oxford
• Pages/Volumes: l, 385 p., [14] p. of plates
• Size: 23 cm
• Classification:
  • DC23 : 615.895
• Subject Headings:
  • LCSH : Gene therapy
  • LCSH : Genetic vectors
  • LCSH : Genetic transformation
• Parent Bibliography ID:
  • BA00197543