Current concepts in drug metabolism and toxicology
Author(s)
Bibliographic Information
Current concepts in drug metabolism and toxicology
（Advances in pharmacology / edited by Silvio Garattini [and] Parkhurst A. Shore, v. 63）
Academic Press, an imprint of Elsevier, 2012
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Description and Table of Contents
Description
This new volume of Advances in Pharmacology explores the current concepts in drug metabolism and toxicology. Chapters cover the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.
Table of Contents
Membrane Transporters in Drug Development
The Keap1-Nrf2 Cell Defence Pathway - A Promising Therapeutic Target?
Animal Models of Idiosyncratic Drug Reactions
Genetic Polymorphisms Affecting Drug Metabolism: Recent Advances and Clinical Aspects
Arylamine N-Acetyltransferases - from Drug Metabolism and Pharmacogenetics to Identification of Novel Targets for Pharmacological Intervention
Human Pluripotent Stem Cells for Modelling Toxicity
Disposition of Biologics
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