Current challenges in personalized cancer medicine

著者

• Smalley, Keiran S. M.

書誌事項

Current challenges in personalized cancer medicine

edited by Keiran S.M. Smalley

（Advances in pharmacology / edited by Silvio Garattini [and] Parkhurst A. Shore, v. 65）

Academic Press, an imprint of Elsevier, 2012

注記

Includes bibliographical references and index

内容説明・目次

内容説明

For this volume of Advances in Pharmacology we have brought together some of the foremost basic science and clinical researchers to discuss some of the new frontiers in the development of targeted cancer therapy. Although still in its formative stages, the development of targeted cancer therapies has already shown incredible promise in a limited number of cancer types. As basic cancer research and drug development continues, we expect this number to grow and more patients to benefit from these exciting advances. Through better patient selection and novel strategies to manage resistance, a future can be envisaged in which cancer can be reduced to the level of a chronic, manageable disease.

目次

Vertical pathway targeting in cancer therapy Histone Deacetylases (HDACs) as Mediators of Resistance to Apoptosis in Melanoma and as Targets for Combination Therapy with Selective BRAF Inhibitors Targeting the tumor stroma as a novel treatment strategy for breast cancer - shifting from the neoplastic cell-centric to a stroma-centric paradigm Targeting the Metabolic Microenvironment of Tumors Targeted Therapy for Matastasis Emerging Strategies for Targeting Cell Adhesion in Multiple Myelom Targeting Notch Signaling for Cancer Therapeutic Intervention Stem-like cells and therapy resistance in squamous cell carcinomas Targeting the tumor stroma as a novel therapeutic approach for prostate cancer Resistance to chemotherapy: short-term drug tolerance and stem cell-like subpopulations Intratumoral Heterogeneity as a Therapy Resistance Mechanism: Role of Melanoma Subpopulations Chemoprevention of Melanoma Whole genome and exome sequencing of melanoma: a step toward personalised targeted therapy Targeted Therapy for Gastric Adenocarcinoma HSP90 Inhibitors for Cancer Therapy and Overcoming Drug Resistance Apoptosis in Targeted Therapy Responses: The Role of BIM

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詳細情報

• NII書誌ID(NCID): BB10480956
• ISBN:
  • 9780123979278
• 出版国コード: ne
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Amsterdam
• ページ数/冊数: xviii, 558 p.
• 大きさ: 24cm
• 件名:
  • LCSH : Cancer -- Treatment
  • LCSH : Electronic books
• 親書誌ID:
  • BA10974234