A structural perspective on respiratory complex I : structure and function of NADH:ubiquinone oxidoreductase
著者
書誌事項
A structural perspective on respiratory complex I : structure and function of NADH:ubiquinone oxidoreductase
Springer, c2012
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The book contains chapters written by leaders in the research on the structure and function of respiratory complex I. It will provide a concise and authoritative summary of the current knowledge on complex I of respiratory chains. This enzyme is central to energy metabolism and is implicated in many human neurodegenerative diseases, as well as in aging. Until recently it was poorly understood on a structural level, and this book will provide a timely reference resource. Such a book was not published previously. The last time a minireview series on complex I were published was in 2001, and since then complex I field changed quite dramatically.
目次
- Foreword
- Leonid Sazanov Part I: Structure and mechanism of complex I 1. Structure of complex I
- Rouslan Efremov and Leonid Sazanov 2. On the mechanism of the respiratory complex I
- Thorsten Friedrich, Petra Hellwig, and Oliver Einsle 3. Iron-sulfur clusters in complex I
- Eiko Nakamaru-Ogiso 4. Current Topics of the Inhibitors of Mitochondrial Complex I
- Hideto Miyoshi 5. My Fifty Years Association with Complex I Study
- Tomoko Ohnishi Part II: Evolution of complex I 6. The Evolutionary Relationship between Complex I and [NiFe]-hydrogenase
- Anne Volbeda and Juan C. Fontecilla-Camps 7. Recruitment of the antiporter module - a key event in complex I evolution
- Vamsi Krishna Moparthi and Cecilia Hagerhall Part III: Mutations in complex I subunits and medical implications 8. Characterization of Bacterial Complex I (NDH-1) by a Genetic Engineering Approach
- Takao Yagi, Jesus Torres-Bacete, Prem Kumar Sinha, Norma Castro-Guerrero, and Akemi Matsuno-Yagi 9. Cellular consequences of mtDNA-encoded mutations in NADH:ubiquinone oxidoreductase
- Mina Pellegrini, Jan A.M. Smeitink, Peter H.G.M. Willems and Werner J.H. Koopman Part IV: Subunit composition and assembly of mitochondrial complex I 10. The assembly of human complex I
- Jessica Nouws, Maria Antonietta Calvaruso, Leo Nijtmans 11. Complexes I in the green lineage
- Claire Remacle, Patrice Hamel, Veronique Larosa, Nitya Subrahmanian, Pierre Cardol Part V: Supercomplexes in mitochondria 12. Supramolecular organization of the respiratory chain
- Janet Vonck Index
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