Drug discovery and evaluation : safety and pharmacokinetic assays
著者
書誌事項
Drug discovery and evaluation : safety and pharmacokinetic assays
(Springer reference)
Springer, c2013
2nd ed
- v. 1 : [hardback]
- v. 2 : [hardback]
大学図書館所蔵 件 / 全3件
-
v. 1 : [hardback]Z491.5||V9285||1WA;1482401887,
v. 2 : [hardback]Z491.5||V9285||2WA;1482401895 -
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注記
Includes bibliographical references
Vol. 2 includes index
内容説明・目次
内容説明
-A landmark in the continuously changing world of drugs
-Essential reading for scientists and managers in the pharmaceutical industry involved in drug finding, drug development and decision making in the development process
-Of use for government institutions and committees working on official guidelines for drug evaluation worldwide
目次
Safety Pharmacokinetics
Absorption / in vitro Tests / Cell Based
Absorption / in vitro Tests / Non Cell Based
Absorption / in vivo Tests (Radiolabeled)
Bioanalytical Assays - RIA/EIA
Bioanalytical Assays / Gas Chromatography (GC)
Bioanalytical Assays / LC-MS/MS
Bioanalytical Assays / Toxicokinetics
Clinical Studies / Typical Designs
Distribution - Across Barriers
Distribution - in vivo - Perfused Organs
Distribution / in vitro Tests / Protein Binding
Distribution / in vivo / Other Methods
Distribution in vivo
Drug-drug Interaction / Enzyme Induction
Drug-drug Interaction / Enzyme Inhibition
In silico ADME Modeling
Metabolism Studies in vitro and in vivo
Pharmacogenomics in DME
Physicochemical Properties
Population Pharmacokinetics
Safety Pharmacokinetics: Introduction
Typical PK/PD Approaches in Preclinical and Clinical Development
Safety Pharmacology
Analgesic Activity and Intravenous and Inhalation Anesthetics
Anti-inflammatory and Antiarthrotic Activity
Biomaterials in Their Role in Creating New Approaches for the Delivery of Drugs, Proteins, Nucleic acids, and Mammalian cells
Blood Constituents
Cardiovascular Pharmacology
Central Nervous System
Chronobiology and the Implications for Safety Pharmacology
Cochlear Safety Tests
Drug Safety on Herbal Medical Products
Drug-Addiction and Drug-Dependency
Endocrine Pharmacology
Magnetic Resonance Imaging and Imaging in Pharmaceutical Safety Assessment
Metabolism Pharmacology
Ocular Safety Tests
Oncology Pharmacology
Peripheral Nervous System
Pulmonary Pharmacology
Renal System
Safe Chemicals / REACH
Safety Pharmacology in Biologics, Antibiotics and Monoclonics
Safety Pharmacology: Introduction and Guidelines
Sensory Systems
Skin Pharmacology
Stem Cells in Safety Pharmacology
Study design and statistics
Transgenic Animals
Zebrafish Model
Safety Toxicology
Genotoxicity
In silico Methods
In vitro toxicity testing
International Guidelines
OMICS Technologies
Reproductive Toxicology
Safety Toxicology: Introduction
Testing of Medical Devices
Testing of Monoclonal Antibodies
Toxicogenomics
Absorption / in vitro Tests / Non Cell Based
Absorption / in vivo Tests (Radiolabeled)
Bioanalytical Assays - RIA/EIA
Bioanalytical Assays / Gas Chromatography (GC)
Bioanalytical Assays / LC-MS/MS
Bioanalytical Assays / Toxicokinetics
Clinical Studies / Typical Designs
Distribution - Across Barriers
Distribution - in vivo - Perfused Organs
Distribution / in vitro Tests / Protein Binding
Distribution / in vivo / Other Methods
Distribution in vivo
Drug-drug Interaction / Enzyme Induction
Drug-drug Interaction / Enzyme Inhibition
In silico ADME Modeling
Metabolism Studies in vitro and in vivo
Pharmacogenomics in DME
Physicochemical Properties
Population Pharmacokinetics
Safety Pharmacokinetics: Introduction
Typical PK/PD Approaches in Preclinical and Clinical Development
Safety Pharmacology
Analgesic Activity and Intravenous and Inhalation Anesthetics
Anti-inflammatory and Antiarthrotic Activity
Biomaterials in Their Role in Creating New Approaches for the Delivery of Drugs, Proteins, Nucleic acids, and Mammalian cells
Blood Constituents
Cardiovascular Pharmacology
Central Nervous System
Chronobiology and the Implications for Safety Pharmacology
Cochlear Safety Tests
Drug Safety on Herbal Medical Products
Drug-Addiction and Drug-Dependency
Endocrine Pharmacology
Magnetic Resonance Imaging and Imaging in Pharmaceutical Safety Assessment
Metabolism Pharmacology
Ocular Safety Tests
Oncology Pharmacology
Peripheral Nervous System
Pulmonary Pharmacology
Renal System
Safe Chemicals / REACH
Safety Pharmacology in Biologics, Antibiotics and Monoclonics
Safety Pharmacology: Introduction and Guidelines
Sensory Systems
Skin Pharmacology
Stem Cells in Safety Pharmacology
Study design and statistics
Transgenic Animals
Zebrafish Model
Safety Toxicology
Genotoxicity
In silico Methods
In vitro toxicity testing
International Guidelines
OMICS Technologies
Reproductive Toxicology
Safety Toxicology: Introduction
Testing of Medical Devices
Testing of Monoclonal Antibodies
Toxicogenomics
Biomaterials in Their Role in Creating New Approaches for the Delivery of Drugs, Proteins, Nucleic acids, and Mammalian cells
Blood Constituents
Cardiovascular Pharmacology
Central Nervous System
Chronobiology and the Implications for Safety Pharmacology
Cochlear Safety Tests
Drug Safety on Herbal Medical Products
Drug-Addiction and Drug-Dependency
Endocrine Pharmacology
Magnetic Resonance Imaging and Imaging in Pharmaceutical Safety Assessment
Metabolism Pharmacology
Ocular Safety Tests
Oncology Pharmacology
Peripheral Nervous System
Pulmonary Pharmacology
Renal System
Safe Chemicals / REACH
Safety Pharmacology in Biologics, Antibiotics and Monoclonics
Safety Pharmacology: Introduction and Guidelines
Sensory Systems
Skin Pharmacology
Stem Cells in Safety Pharmacology
Study design and statistics
Transgenic Animals
Zebrafish Model
Safety Toxicology
Genotoxicity
In silico Methods
In vitro toxicity testing
International Guidelines
OMICS Technologies
Reproductive Toxicology
Safety Toxicology: Introduction
Testing of Medical Devices
Testing of Monoclonal Antibodies
Toxicogenomics
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