Diversity and functions of GABA receptors: a tribute to Hanns Möhler
著者
書誌事項
Diversity and functions of GABA receptors: a tribute to Hanns Möhler
(Advances in pharmacology / edited by Silvio Garattini [and] Parkhurst A. Shore, v. 72-73)
Academic Press, an imprint of Elsevier, 2015
- pt. A
- pt. B
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注記
Includes bibliographical references and index
Series editor: S. J. Enna
Managing editor: Lynn Lecount
内容説明・目次
- 巻冊次
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pt. B ISBN 9780128026588
内容説明
Diversity and Functions of GABA Receptors: A Tribute to Hanns Moehler, Part B, a new volume of Advances in Pharmacology, presents the diversity and functions of GABA Receptors. The volume looks at research performed in the past 20 years, which has revealed specific physiological and pharmacological functions of individual GABAA receptor subtypes, providing novel opportunities for drug development.
目次
1. Reflections on more than 30 years Association with HannsNorman G. Bowery2. Significance of GABAA Receptor Heterogeneity: Clues from Developing NeuronsJean-Marc Fritschy3. Regulation of Cell Surface GABAB Receptors: Contribution to Synaptic Plasticity in Neurological DiseasesDietmar Benke, Karthik Balakrishnan and Khaled Zemoura4. Restoring the Spinal Pain Gate: GABAA Receptors as Targets for Novel AnalgesicsHanns Ulrich Zeilhofer, William T. Ralvenius and Mario A. Acuna5. GABAergic Control of Depression-related Brain States Bernhard Luscher and Thomas Fuchs6. Mechanisms of Fast Desensitization of GABAB Receptor-Gated CurrentsAdi Raveh, Rostislav Turecek and Bernhard Bettler7. Allosteric Ligands and their Binding Sites Define ?-Aminobutyric acid (GABA) Type A Receptor SubtypesRichard W. Olsen8. Diversity in GABAergic SignalingKaspar Vogt9. The Diversity of GABAA Receptor Subunit Distribution in the Normal and Huntington's Disease Human BrainHJ Waldvogel and RLM Faull
- 巻冊次
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pt. A ISBN 9780128026601
内容説明
This new volume of Advances in Pharmacology presents the diversity and functions of GABA Receptors. The volume looks at research performed in the past 20 years which has revealed specific physiological and pharmacological functions of individual GABAA receptor subtypes, providing novel opportunities for drug development.
目次
1. The Legacy of the Benzodiazepine Receptor: From Flumazenil to Enhancing Cognition in Down Syndrome and Social Interaction in Autism
Hanns Moehler
2. Behavioral Functions of GABAA Receptor Subtypes - the Zurich Experience
Florence Crestani and Uwe Rudolph
3. Allosteric Modulation of GABAA Receptors via Multiple Drug Binding Sites
Werner Sieghart
4. Regulation of GABAARs by Phosphorylation
Yasuko Nakamura, Laura M. Darnieder, Tarek Z. Deeb and Stephen J. Moss
5. Endozepines
Zoya Farzampour, Richard J. Reimer and John Huguenard
6. Inhibitory Neurosteroids and the GABAA Receptor
Sandra Seljeset, Duncan Laverty and Trevor G Smart
7. Interactions of Flavonoids with Ionotropic GABAA Receptors
Jane R Hanrahan, Mary Chebib and Graham A R Johnston
8. GABAA Receptor Partial Agonists and Antagonists: Structure, Binding Mode, and Pharmacology
Jacob Krall, Thomas Balle, Niels Krogsgaard-Larsen, Troels E. Sorensen, Povl Krogsgaard-Larsen, Uffe Kristiansen and Bente Frolund
9. Closing the Gap between the Molecular and Systemic Actions of Anesthetic Agents
Bernd Antkowiak
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