Pharmacological assays of plant-based natural products

著者
    • Thangaraj, Parimelazhagan
書誌事項

Pharmacological assays of plant-based natural products

Parimelazhagan Thangaraj

(Progress in drug research / edited by Ernest Jucker, 71)

Springer, c2016

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This volume provides information on how to select and screen plants for their medicinal properties. It describes phytopharmacological techniques for extracting and qualitatively and quantitatively analyzing a plant's phytochemicals. After a detailed in vitro investigation including nutritional and anti-nutritional analyses, medicinal properties were tested with various in vivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer and anti-diabetic properties, as well as wound healing, neurodegenerative diseases, etc. Compound identification and purification techniques include, among others, TLC and column chromatography, as well as molecular docking with specific proteins.

目次

1. Extraction of plant material.- 2. Critical aspects of purification and impurities in natural product extracts. 3. In vitro antioxidant assays.- 4. In vivo antioxidant assays.- 5. Quantification assays.- 6. Anti-nutritional factors.- 7. Anti-inflammatory activity.- 8. Antipyretic activity.- 9. Inflammation bowel disease.- 10. Anti-arthritic activity.- 11. Evaluation of analgesic potential.- 12. Anti-diarrhoeal activity.- 13. Anti-ulcer activity.- 14. In vitro anti-diabetic activity.- 15. In vivo anti-diabetic activity.- 16. Hepatoprotective property.- 17. Antitumor activity.- 18. In vivo wound healing studies.- 19. Determination of cytotoxicity.- 20. Evaluation of bioavailability.- 21. Molecular identification by DNA barcoding.- 22. Molecular docking of bioactive compounds against BRCA and COX proteins.

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関連文献: 1件中  1-1を表示
  • Progress in drug research

    edited by Ernest Jucker

    Birkhäuser 1998-

    v. 50 , v. 51 , v. 52 , v. 53 , v. 54 , v. 55 , v. 56 , v. 57 , v. 58 , v. 59 , Special topic , v. 60 , v. 61

    所蔵館9館

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