Protein-protein interactions in human disease
著者
書誌事項
Protein-protein interactions in human disease
（Advances in protein chemistry and structural biology, v. 110,
Academic Press, an imprint of Elsevier, 2018
- pt. A
- pt. B
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注記
Includes bibliographical references
内容説明・目次
- 巻冊次
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pt. B ISBN 9780128143421
内容説明
Protein-Protein Interactions in Human Disease, Volume 111, Part B, promotes further research and development in the protein interaction network in order to identify critical proteins involved in the etiology of human diseases and locate new protein targets for drug development. Thus, this volume is of considerable interest to protein chemists, pharmacologists, cell biologists, immunologists, structural biologists, computational biochemists and other researchers working in the field. In addition, these articles would be of great benefit to medical, biology and pharmacology students who specialize in this field.
目次
1. Homo- and Heterodimerization of Proteins in Cell Signaling: Inhibition and Drug DesignSitanshu S. Singh and Seetharama D. Jois2. Targeting Intramembrane Protein-Protein Interactions: Novel Therapeutic Strategy of Millions Years OldAlexander B. Sigalov3. Targeting the Architecture of Deregulated Protein Complexes in CancerEduard Stefan, Jakob Troppmair and Klaus Bister4. Multifaceted Nucleolin Protein and Its Molecular Partners in OncogenesisIva Ugrinova, Maria Petrova, Mounira Chalabi-Dchar and Philippe Bouvet5. Subcellular Targeting of Nitric Oxide Synthases Mediated by Their N-Terminal MotifsCarlos Costas-Insua, Javier Merino-Gracia, Clara Aicart-Ramos and Ignacio Rodriguez-Crespo6. Development of Protein-Protein Interaction Inhibitors for the Treatment of Infectious DiseasesAndrew F. Voter and James L. Keck7. Defining Pharmacological Targets by Analysis of Virus-Host Protein InteractionsManuel Llano and Mario A. Pena-Hernandez8. Investigating the Influence of Hotspot Mutations in Protein-Protein Interaction of IDH1 Homodimer Protein: A Computational ApproachD. Thirumal Kumar, P. Sneha, Jennifer Uppin, S. Usha and C. George Priya Doss9. Human Interactomics: Comparative Analysis of Different Protein Interaction Resources andConstruction of a Cancer Protein-Drug Bipartite NetworkJavier De Las Rivas, Diego Alonso-Lopez and Monica M. Arroyo
- 巻冊次
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pt. A ISBN 9780128143445
内容説明
Protein-Protein Interactions in Human Disease, Part A, Volume 110 aims to promote further research and development in the protein interaction network as a means to not only identify the critical proteins involved in the etiology of human diseases, but also identify new protein targets for drug development. Sections cover such topics as protein-protein interaction modulators for epigenetic therapies, intrinsic disorder, protein-protein interactions and disease, targeting protein-protein interactions in the ubiquitin-proteasome pathway, the proteomics of occupational diseases, and computational methods in predicting the impact of SNPs in protein-protein network, amongst other topics.
目次
1. Analysis of protein interactions by surface plasmon resonance Dennis G. Drescher 2. Using TR-FRET to investigate protein-protein interactions: a case study of PXR-coregulator interaction Taosheng Chen 3. Protein-Protein Interaction Modulators for Epigenetic Therapies Jose L. Medina-Franco 4. Intrinsic disorder, protein-protein interactions and disease Vladimir N. Uversky 5. Targeting protein-protein interactions in the ubiquitin-proteasome pathway Maria Gaczynska 6. Protein-protein networks involved in MODY family George Priya Doss P. C 7. Defining HIV-1 replication mechanisms by analyzing virus-host protein interactions Manuel Llano 8. Proteomics of occupational diseases Nicola Luigi Bragazzi 9. Proteomics of sport-related injuries Nicola Luigi Bragazzi 10. Structural prediction of protein-protein interactions by docking: application to biomedical problems Juan Fernandez-Recio 11. Computational methods in predicting the impact of SNPs in Protein-protein network George Priya Doss P. C
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