Thermoregulation : from basic neuroscience to clinical neurology
著者
書誌事項
Thermoregulation : from basic neuroscience to clinical neurology
（Handbook of clinical neurology, . 3rd ser. ; 156-157）
Elsevier, c2018
- pt. 1
- pt. 2
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内容説明・目次
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pt. 1 ISBN 9780444639127
内容説明
Thermoregulation, Part I: From Basic Neuroscience to Clinical Neurology, Volume 154, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function.
In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions.
目次
SECTION I. THERMOREGULATION SYSTEM 1. The thermoregulation system and how it works
SECTION II. THERMORECEPTORS 2. Peripheral thermoreceptors in innocuous temperature detection 3. Molecular basis of peripheral innocuous cold sensitivity 4. Molecular basis of peripheral innocuous warmth sensitivity 5. Peripheral and central determinants of skin wetness sensing in humans 6. Nociceptors. Thermal allodynia and thermal pain 7. Central thermoreceptors 8. Molecular Basis of Central Thermosensation
SECTION III. THERMOEFFECTORS 9. Brown adipose tissue as a heat-production thermoeffector 10. Shivering and nonshivering thermogenesis in skeletal muscles 11. Skin vasoconstriction as a heat-conservation thermoeffector 12. Cutaneous active vasodilation as a heat-loss thermoeffector 13. Sweating as a heat-loss thermoeffector 14. Panting as a heat-loss thermoeffector 15. Thermal comfort
SECTION IV. NEURAL PATHWAYS 16. Afferent pathways for autonomic and shivering thermoeffectors 17. Efferent neural pathways for the control of brown adipose tissue thermogenesis and shivering 18. Efferent thermoregulatory pathways regulating cutaneous blood flow and sweating 19. Central neural substrates involved in temperature discrimination, thermal pain, thermal comfort, and thermoregulatory behavior
SECTION V. THERMOREGULATION AS A HOMEOSTATIC FUNCTION 20. Body temperature and sleep 21. Skin Temperature, Sleep and Vigilance 22. Thermoregulation and the ultradian basic rest-activity cycle 23. Thermoregulation and age 24. Temperature and adaptive immunity 25. Interactions between body fluid homeostasis and thermoregulation in humans 26. Obesity and Thermoregulation 27. Thermoregulation and nausea 28. Neurogenesis in the thermoregulatory system
- 巻冊次
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pt. 2 ISBN 9780444640741
内容説明
Thermoregulation, Part II: From Basic Neuroscience to Clinical Neurology, Volume 155, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function.
In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions.
目次
SECTION VI. Normal and abnormal body core and peripheral temperatures 29. Body temperature and clinical thermometry 30. Brain Temperature: From Physiology and Pharmacology to Neuropathology 31. Heat exhaustion 32. Heatstroke 33. Accidental hypothermia 34. Fever and hypothermia in systemic inflammation 35. Stress-induced hyperthermia and hypothermia 36. Body temperature regulation and drugs of abuse 37. Body temperature regulation and anesthesia 38. Malignant hyperthermia 39. Neuroleptic malignant syndrome and serotonin syndrome 40. Acral coldness - severely reduced blood flow to fingers and toes 41. Consequences of Perioperative Hypothermia
SECTION VII. THERMOREGULATION IN NEUROLOGICAL DISEASE 42. Thermoregulatory Dysfunction in Multiple Sclerosis 43. Thermoregulation in Parkinson disease 44. Hypothermia as a risk factor for Alzheimer disease 45. Thermoregulation in epilepsy 46. Thermoregulation in amyotrophic lateral sclerosis 47. Thermoregulatory Disorders in Huntington's Disease 48. Thermoregulation in neuropathies 49. Thermoregulation in brain injury 50. Thermoregulation Following Spinal Cord Injury
SECTION VIII. THERAPEUTIC INTERVENTIONS 51. Hypothermia in Acute Ischemic Stroke Therapy 52. Selective brain hypothermia 53. Therapeutic hyperthermia 54. Antipyretic therapy: Clinical pharmacology
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