Leydig cells : structure, functions and clinical aspects
著者
書誌事項
Leydig cells : structure, functions and clinical aspects
（Cell biology research progress series）
Nova Science Publishers, c2020
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The main function of the Leydig cells is to synthesize testosterone, but growing evidence supports the idea that Leydig cells are important in regulating the testicular immune environment. As such, Leydig Cells: Structure, Functions and Clinical Aspects discusses Leydig cells serving as immunological sentinels in the testis. Next, the authors explore the commercially available immortalized Leydig cell lines (TM3, R2C, MA-10 and MLTC-1) derived from rat or mouse and the results of studies using these cells. Additionally, the effects of the most commonly used environmental contaminants on Leydig cell function are discussed in the context of the impaired of steroidogenic pathway. The results of several studies are presented which demonstrate that lycopene supplementation improves and maintaines the normal level of testosterone by improving the expression of StAR protein and steroidogenic enzymes in the Leydig cells of polychlorinated biphenyl exposed rats.
目次
PrefaceImmunological Function of Leydig CellsLeydig Cell Lines: In Vitro Models for Testosterone BiosynthesisThe Role of Environmental Contaminants in Leydig Cell SteroidogenesisEffect of Endocrine Disruptors (PCBs/DEHP) on Testicular Leydig Cells in Adult and f1 Male Offspring RatsBibliographyIndex.
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