Genome analysis : a practical approach
著者
書誌事項
Genome analysis : a practical approach
（The practical approach series）
IRL Press, 1988
- : hard
- : pbk.
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注記
Includes bibliographies and index
内容説明・目次
- 巻冊次
-
: hard ISBN 9781852211097
内容説明
Includes : Techniques for mammalian genome transfer; genome mapping by restriction fingerprinting; pulsed field gel electrophoresis and the technology of large DNA molecules; chromosome jumping; the polymerase chain reaction; DNA fingerprinting; mapping complex genetic traits in humans This book is intended for postgraduates and researchers in molecular biology, biochemistry.
目次
- Abbreviations
- P.N. Goodfellow, C.A. Pritchard, & G.S. Banting: Techniques for mammalian genome transfer
- A. Coulson & J. Sulston: Genome mapping by restriction fingerprinting
- C.L. Smith, S.R. Klco, & C.R. Cantor: Pulsed-field gel electrophoresis and the technology of large DNA molecules
- F.S. Collins: Chromosome jumping
- R.M. Myers, V.C. Sheffield, & D.R. Cox: Detection of single base changes in DNA: ribonuclease cleavage and denaturing gradient gel electrophoresis
- R.K. Saiki, U.B. Gyllensten, & H.A. Erlich: The polymerase chain reaction
- R.A. Wells: DNA fingerprinting
- E.S. Lander: Mapping complex genetic traits in humans
- Index
- 巻冊次
-
: pbk. ISBN 9781852211103
内容説明
Methodologies used to analyse the genomes of prokaryotes and eukaryotes are advancing very rapidly as it has been realized that there is a resolution gap between what can be viewed under the microscope and what molecular techniques can resolve. This book presents current, successful strategies for construction of physical maps to identify and analyse the arrangement and function of genes. These techniques, which are applicable to a range of organisms, are being used to move from linked markers to candidate genes in several human monogenic disorders. They are presented in a way that should enable any research or diagnostic laboratory to apply them to their particular systems. Also included are descriptions of new probes and approaches for the localization of human disorders whose analysis has so far eluded the molecular geneticist.
目次
- Goodfellow: Techniques for mammalian genome transfer
- Coulson: Genome mapping by restriction fingerprinting
- Smith: Pulsed-field gel electrophoresis and the technology of large DNA molecules
- Collins: Chromosome jumping
- Myers: Detection of single base changes in DNA
- Saiki: The polymerase chain reaction
- Wells: DNA fingerprinting
- Lander: Mapping complex genetic traits in humans
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