Circumventricular organs and brain fluid environment : molecular and functional aspects
著者
書誌事項
Circumventricular organs and brain fluid environment : molecular and functional aspects
(Progress in brain research, v. 91)
Elsevier, 1992
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This volume provides a picture of the state of the art and of the perspectives opened by new powerful approaches to the study of the structure and function of "Circumventricular Organs" (CVOs). Studies on the CVOs reflected in this book comprise many aspects, from cellular elements to the whole organism: the accessibility of these organs for chemical signals, signal (ligand)-receptor interactions, the transfer of information to distinct brain regions, the effects induced in these brain regions and the influence on the regulation of body functions including autonomic and behavioral alterations. Some of these aspects strongly depend upon the microenvironment of the cells involved in this cascade of events. Therefore, the brain fluid environment in its broadest sense is a central focus. This excellent work is therefore an up-to-date report on interdisciplinary approaches and concepts, offering new insights into the complex phenomena of brain function, and shows directions in which to proceed.
目次
List of contributors. Preface. Acknowledgements. Section I - Microenvironment of the brain: blood - interstitial fluid - CSF. 1. A role for centrally-released vasopressin in brain ion and volume regulation: an hypothesis. 2. Neuronal plasticity depending on a glycoprotein synthesized in goldfish leptomeninx. 3. Goldfish ependymins: cerebrospinal fluid proteins of meningeal origin. 4. Effect of central administration of angiotensin II on cerebrospinal fluid formation in rabbits. 5. Adrenalectomy aggravates ischemic brain edema in female Sprague-Dawley rats with carotid arteries ligated. 6. Central release of vasopressin: stimuli, dynamics, consequences. 7. Pregnancy and opiod interactions with the anterior peri-third ventricular input to magnocellular oxytocin neurones. 8. Endogenous opioids regulate intracerebral oxytocin release during parturition in a region-specific manner. 9. Evidence against participation of V2 receptors in the increase of cerebral blood flow during hypoxemia in the rat. 10. ANF-induced modulation of ADH-release in the rabbit and pekin duck. 11. Vasopressin involvement in central control of blood pressure. 12. Neuropeptides within the nucleus tractus solitarii modulate the central cardiovascular control process. 13. Disturbances of volume regulation in chronic alcoholics: a correlation with the excitability of the central nervous system. 14. Chromatographically identified oxytocin in human peripheral nervous system. 15. Central effects of tricyclic compounds on the endocrine system - an in vitro system. Section II - Barriers within the brain: transport - exchange. 16. Intracerebral grafting of solid tissues and cell suspensions: the blood-brain barrier and host immune response. 17. Blood-brain barrier: a molecular approach to its structural and functional characterization. 18. Development of an in vitro cell culture system to mimic the blood-brain barrier. 19. The development of ion regulation at the blood-brain barrier. 20. An approach to study of transport of trace metals at the blood-brain barrier. 21. Bidirectional passage of peptides across the blood-brain barrier. 22. Localization patterns for immunoglobulins and albumins in the brain suggest diverse mechanisms for their transport across the blood-brain barrier. 23. Peptide receptors of the blood-brain barrier and substrate transport into the brain. 24. The interaction of some centrally active drugs with the blood-brain barrier and circumventricular organs. 25. Experimental models of altering the blood-brain barrier. 26. Regulation of transendothelial transport in the cerebral microvessels: the role of second messenger's-generating system. 27. Age-related pathophysiology of the blood-brain barrier in heat stress. 28. Endogenous release of neurochemicals may increase vascular permeability, induce edema and influence on cell changes in trauma to the spinal cord. 29. Tracer upstake by circumventricular organs - A relative measure of blood supply to the brain. 30.
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