Dementia
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書誌事項
Dementia
Chapman & Hall Medical, 1994
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内容説明・目次
内容説明
Dementia is one of the most important clinical conditions in modern medicine. In the elderly, it is a common condition, numerically dwarfing other, better known, diseases. Advances in the last decade have been numerous both in the breadth of clinical assessment of patient, the use of adjuvant investigations and significantly in the basic biology of a number of disorders. This book attempts a comprehensive review of dementia in one volume. Attention is paid both to the clinical syndrome of demential and the specific disorders which underlie the condition. The book is divided into two main parts - Alzheimer's disease and other dementias. The first consists of chapters covering epidemiology, aetiology, clinical aspects, neuropathology, neurochemistry and molecular biology, neuroadiology, neurophysiology and treatment aspects. The second covers vascular dementia and includes chapters on dementias associated with psychiatric conditions (for example depression and paraphenia), neurological disorders (for example Parkinson's disease and Huntington's disease) as well as other diseases such as Pick's disease, frontal lobe dementia and progressive focal syndromes.
The complications of alcoholism and AIDS are also included as is a chapter on dementias. The book is written by experts in the field and presents an up-to-date digest of the most important aspects of dementia. Clinicians should find information about basic science and scientists should find understandable accounts of the clinical syndromes. The book should appeal to those interested in the syndrome of dementia and its causes.
目次
Dementia of the Alzheimer Type.- Dementia: Historical Overview.- The Scale of the Problem.- The Differential Diagnosis of Dementia.- Cognitive and Noncognitive Aspects of Dementia Syndromes: An Overview.- Longitudinal Changes in Cognition.- Survival in Alzheimer's Disease.- Subtypes of Alzheimer's Disease.- Heterogeneity in Alzheimer's Disease: A European View.- Risk Factors for Dementia.- Cholinergic Component of Cognitive Impairment in Dementia.- Abnormalities in Non-Cholinergic Neurotransmitter Systems in Alzheimer's Disease.- The Neuropathology of Alzheimer's Disease.- Molecular Pathobiology of Alzheimer's Disease.- Animal Models of Alzheimer's Disease.- The Role of Aluminium in Dementia of Alzheimer's Type: A Review of the Hypotheses and Summary of the Evidence.- Genetic Factors.- Benign Senescent Forgetfulness and Age Associated Memory Impairment.- The Clinical Diagnosis of Alzheimer's Disease.- Neuropsychological Investigations of Dementia.- Rating Scales.- The Neurophysiology of Dementia.- Peripheral Markers in Alzheimer's Disease.- Computed Tomography.- Magnetic Resonance Imaging and Spectroscopy in Dementia.- Single Photon Emission Tomography.- Positron Emission Tomography.- Nerve Growth Factor and Other Biological Treatments: An Overview.- Non-Cholinergic Therapies of Dementia.- Cholinergic Treatment of Alzheimer's Disease.- Treatments for Psychiatric Symptoms and Behavioral Disturbances in Dementia.- Management of the Family.- Psychological Treatments.- Services for Dementia: A British View.- Dementia Services: A Continental European View.- North American Services for Patients with Dementia.- Psychogeriatric Services to Demented Elderly in Japan.- Dementia Services: An Australian View.- Non-Alzheimer Dementia.- Vascular Dementia: Definitions, Epidemiology and Clinical Features.- Leukoaraiosis.- Vascular Dementia: Pathological Findings.- Depression Induced Cognitive Impairment.- Dementia Associated with Alcohol.- Down's Syndrome and Dementia of the Alzheimer Type.- Cognitive Changes in Late Paraphrenia.- Dementia in Parkinson's Disease and Lewy Body Disease.- Pick's Disease.- Huntington's Disease.- Acquired Immunodeficiency Syndrome (AIDS).- Cognitive Dysfunction in Multiple Sclerosis.- Unusual Forms of Dementia.- Dementia of Frontal Lobe Type.- Progressive Aphasia and Other Focal Syndromes.- Prion Diseases.
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