Functional neural transplantation II. novel cell therapies for CNS disorders
著者
書誌事項
Functional neural transplantation II. novel cell therapies for CNS disorders
(Progress in brain research, v. 127)
Elsevier, 2000
大学図書館所蔵 全22件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographies and index
内容説明・目次
内容説明
The first edition of Functional Neural Transplantation, appearing in 1994, was commissioned to provide a systematic overview of the main areas of active research into the use of neural transplantation for functional repair at that time. There have though been major developments in the field over the last decade. First, whereas many of the model systems are the same, the sophistication of the research has developed dramatically. Secondly, there has been a major change in focus related to the nature of the optimal reparative process, moving away from a primary goal involving repair by replacement of lost cells, to strategies based on halting or reversing the disease process itself. Thirdly, the last decade has (not surprisingly) seen an expansion in the breadth of clinical applications for transplantation not only of primary embryonic neural tissues but also the initial applications of cells and cell lines.In order to address these recent developments as we enter the 21st century, 10 years after conception and 6 years after the publication of Functional Neural Transplantation, the Editors have now sought to co-ordinate and edit an updated version, Functional Neural Transplantation II.Functional Neural Transplantation II is not just a revised edition of the previous volume, but an entirely new and complementary second volume to update the field to 'state of the art' for the new millennium. For many major topic areas (such as functional repair in neurodegenerative disorders of the basal ganglia) there has been a continual flow of significant advances. Although these topics are covered in both volumes, the Editors have sought to avoid duplication by requiring that the present coverage emphasises the major developments over the last decade while relying on the first volume for the background overviews. Other topics though are entirely new in the present volume, such as novel applications of neural transplantation to other major clinical relevance such as retinal repair or alleviation of pain. A key departure of the present volume is the addition of several early chapters addressing the technical and developmental issues associated with identification of alternative sources of cells for transplantation - cell lines, immortalised cells, precursor/stem cells and xenotransplantation.
目次
List of contributors. Preface. 1. The subventricular zone: source of neuronal precursors for brain repair (A.Alvarez-Buylla, D.G. Herrera and H. Wichterle). 2. Neural stem cells in the developing central nervous system: implications for cell therapy through transplantation (C.N. Svendsen and M.A. Caldwell). 3. Activity-dependent regulation of neuronal plasticity and self repair (G. Kempermann, H. van praag and F.H. Gage). 4. Immortalized neural cell lines for CNS transplantation (S.R. Whittemore and S.M. Onifer). 5. The chick/quail transplantation model to study central nervous system development (R.-M. Alvarado-Mallart). 6. Novel mechanisms in mammalian telencephalic development as revealed by neural transplantation ( K. Campbell and M. Olsson). 7. Reconstruction of cortical circuitry (M.A. Gates, R.A. Fricker and J.D. Macklis). 8. Xenotransplantation (E.B. Pedersen and H. Widner). 9. Encapsulated neural transplants (J.L. Tseng and P. Aebischer). 10. Improving the survival of grafted embryonic dopamine neurons in rodent models of Parkinson's disease (R.F. Castillo, O.Hansson and P. Brundin). 11. Transplantation in the rat model of Parkinson's disease: ectopic versus, homotopic graft placement (C. Winkler, D. Kirik, A. Bjoerklund and S.B. Dunnett). 12. The primate model of Parkinson's disease: its usefulness, limitations, and importance in directing future studies (K.D. Bingaman and R.A.E. Bakay). 13. Clinical observations after neural transplantation in Parkinson's disease (O. Lindvall and P. Hagell). 14. Non-invasive in vivo imaging of transplant function (D.J. Brooks and P. Piccini). 15. Neurophatology of fetal nigra transplants for Parkinson's disease (J.H. Kordower and C.E. Sortwell). 16. The integration and function of striatal grafts (S.B. Dunnett, F. Nathwani and a. Bjoerklund). 17. Striatal tissue transplantation in non-human primates (A.L. Kendall, P. Hantraye and S. Palfi). 18. Neural transplantation for the treatment of Huntington's disease (T.B. Freeman, R.A. Hauser, P.R. Sanberg and S. Saporta). 19. Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible? (J.H. Kordower, O. Isacson, L. Leventhal and D.F. Emerich). 20. Functional reconstruction of the hippocampus (R.M. Ridley, H.F. Baker and H. Hodges). 21. Restoration of function by neural transplantation in the ischemic brain (H. Nishino and C.V. Borlongan). 22. Functional aspects of cerebellar transplantation (L.C. Triarhou). 23. Preservation and restoration of vision following transplantation (P.J. Coffey, S.J.O. Whiteley and R.D. Lund). 24. Spinal cord motoneuron maintenance, injury and repair (T. Carlstedt and S. Cullheim). 25. Remyelination and restoration of axonal function by glial cell transplantation (S.-C. Zhang and I.D. Duncan). 26. The alleviation of pain by cell transplantation (I.D. Hentall and J. Sagen).
「Nielsen BookData」 より