Description
First published in 1942, "Wintrobe's Clinical Hematology" continues its tradition of excellence in correlating basic science with the clinical practice of hematology. This is the most comprehensive hematology book on the market and is organized to help physicians find clinical answers quickly and easily. The Eleventh Edition places a greater emphasis on clinical hematology, especially molecular aspects and new therapies. Most chapters have been revised or reconfigured, and seven new chapters have been added: Gene Therapy, Congenital Immunodeficiency Syndromes, Acute Lymphocytic Leukemia in Adults, Acute Myelogenous Leukemia in Children, Acute Promyelocytic Leukemia, Systemic Mastocytosis, and Diagnosis and Classification of Lymphoproliferative Disorders.
Table of Contents
Part 1. Laboratory Hematology 1. Examination of Blood and Bone Marrow 2. Clusters of Differentiation 3. Clinical Flow Cytometry 4. Cytogenetics 5. Molecular Genetics and Hematology Part 2. The Normal Hematologic System 6. Origin and Development of Blood Cells 7. Erythropoiesis 8. The Mature Erythrocyte 9. Destruction of Erythrocytes 10. Neutrophilic Leukocytes 11. The Human Eosinophils 12. Basophilic Leukocytes: Mast Cells and Basophils 13. Mononuclear Phagocytes 14. Phagocytosis 15. The Lymphatic System 16. B Lymphocytes 17. T Lymphocytes and NK Cells 18. Cell Interactions in the Immune Response 19. Platelets and Megakaryocytes 20. Platelet Function in Hemostasis and Thrombosis 21. Blood Coagulation and Fibrinolysis 22. Endothelium and the Regulation of Hemostasis Part 3. Therapeutic Modalities 23. Red Cell, Platelet, and White Cell Antigens 24. Transfusion Medicine 25. Hematopoietic Stem Cell Transplantation 26. Gene Therapy Part 4. Disorders of Red Cells 27. Diagnostic Approach to Anemia 28. Iron Deficiency and Related Disorders 29. Sideroblastic Anemias 30. Hemochromatosis 31. Porphyria 32. Hemolytic Disorders: General Considerations 33. Hereditary Spherocytosis and Other Anemias Due to Abnormalities 34. Hereditary Hemolytic Anemias Due to Enzyme Abnormalities 35. Alloimmune Hemolytic Disease of the Fetus and Newborn 36. Autoimmune Hemolytic Anemias 37. Paroxysmal Nocturnal Hemoglobinuria 38. Acquired Non-Immune Hemolytic Disorders 39. The Abnormal Hemoglobins: General Principles 40. Sickle Cell Anemia and Other Sickling Syndromes 41. Unstable Hemoglobin Disease 42. The Thalassemias and Related Disorders: Quantitative Disorders 43. Megaloblastic Anemias: Disorders of Impaired DNA Synthesis 44. Acquired and Congenital Aplastic Anemia Syndromes 45. Pure Red Cell Aplasia in Children and Adults 46. Congenital Dyserythropoietic Anemias 47. Anemias Secondary to Chronic Disease and Systemic Disorders 48. Anemias Unique to Pregnancy and the Perinatal Period 49. Methemoglobinemia 50. Erythrocytosis Part 5. Disorders of Hemostasis and Coagulation 51. The Diagnostic Approach to the Bleeding Disorders 52. Thrombocytopenia: Pathophysiology/Classification 53. Thrombocytopenia Caused by Immunolgic Platelet Destruction 54. Thrombotic Thrombocytopenic Purpura and Other Formsa 55. Miscellaneous Causes of Thrombocytopenia 56. Bleeding Disorders Caused by Vascular Abnormalities 57. Thrombocytosis 58. Qualitative Disorders of Platelet Function 59. Inherited Coagulation Disorders 60. Acquired Coagulation Disorders 61. Thrombosis and Antithrombotic Therapy Part 6. Nonmalignant Disorders of Leukocytes, the Spleen, and/or Immunoglobins 62. Diagnostic Approach to Disordersa 63. Neutropenia 64. Qualitative Disorders of Leukocytes 65. Abnormalities of the Monocyte-Macrophage System--The Lysosomala 66. Langerhans Cell Histiocytosis 67. Infectious Mononucleosis and Other EBV-Related Disorders 68. Congenital Immune Deficiencies 69. Acquired Immunodeficiency Disease 70. D
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