Neurological disorders in systemic cancer
著者
書誌事項
Neurological disorders in systemic cancer
（Handbook of clinical neurology, v. 69 = rev. ser. 25 . Neuro-oncology ; pt. 3）
Elsevier, c1997
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This volume, the third part of Neuro-Oncology is, in a comprehensive and multidisciplinary approach, devoted to the theme of "Neurological Disorders in Systemic Cancer", focusing on issues confronting neurologists in their daily practice. Metastatic disease of the nervous system afflicts about a quarter of all patients with cancer. One chapter is devoted entirely to the origin and mechanisms causing metastatic disease of the nervous system. The neurological complications of hematological neoplasms, including the leukemias, lymphomas, and paraproteinemias, are reviewed in depth, as is the stunning progress made in unravelling the mechanisms of paraneoplastic syndromes of the nervous system. For this intriguing group of disorders, separate attention has been paid to the underlying changes in molecular biology, to the general diagnostic approach and to the characteristics of each of the paraneoplastic syndromes of the central and peripheral nervous system, often associated with specific tumors. All aspects of these disorders are extensively covered in this volume, providing the reader with a working knowledge and useful reference system for understanding the spectrum of neurological disorders that may develop in systemic cancer. Neuro-Oncology will assist the clinical neurologist and other specialists dealing with nervous system complications of cancer in arriving at a well-defined diagnosis and establishing an effective and thoughtful management plan.
目次
Foreword. List of contributors.
I. Clinical Features in Neuro-oncology.
1. Prevalence of neurologic disease in cancer (P.D. Clouston). 2. Epilepsy in the cancer patient (M. Glantz, L.D. Recht). 3. Headache in the cancer patient (A. Demchuk, P. Forsyth). 4. Pain in cancer (P.L.I. Dellemijn, Ch. J. Vecht). 5. Back pain in the cancer patient (S.M. Weinstein, R.K. Portenoy). 6. Malignant radiculopathy and plexopathy (J.P. Stubgen, K.J. Elliott).
II. Cns Metastasis Of Solid Tumors.
7. Metastasis to the brain: cellular and molecular mechanisms (M. Mareel, A. Leroy, M. Bracke). 8. Dural, calvarial and skull base metastasis (R.A. Rodas, H.S. Greenberg). 9. Brain metastasis (R.A. Patchell). 10. Leptomeningeal metastases (M.C. Chamberlain). 11. Metastatic spinal cord compression (R. Lada, H.J. Kaminski, R.L. Ruff). 12. Central nervous system metastasis in breast cancer (W. Boogerd). 13. CNS prophylaxis of small cell lung cancer (A. Twijnstra).
III. Neurological Complications Of Hematological Neoplasms
14. Neurological complications of leukemia (H. Haaxma-Reiche). 15. Neurological complications of systemic lymphoma (M.J. Van den Bent). 16. Neurological complications of paraproteinemias (P.K. Richardson, J.J. Kelly, Jr.).
IV. Paraneoplastic Syndromes Of The Nervous System.
17. Paraneoplastic syndromes of the nervous system: diagnostic approaches (J. Dalmau). 18. Molecular biology of paraneoplastic neurological syndromes (P.A.E. Sillevis Smitt, G.T. Manley). 19. Paraneoplastic syndromes of the central nervous system (J.W.B. Moll, Ch.J. Vecht). 20. Paraneoplastic syndromes of the peripheral nervous system (M.R. Rosenfeld, J. Verschuuren, J. Dalmau).
V. Non-Metastatic Complications In Neuro-Oncology.
21. Metabolic nervous system dysfunction in cancer (R.H. Boerman, G.W. Padberg). 22. Neurovascular complications of solid tumors and hematological neoplasms (L.R. Rogers). 23. Opportunistic CNS infections in cancer (R.H. Boerman, B.J. Kullberg). 24. Chemotherapy-induced peripheral neuropathy (T.J. Postma, J.J. Heimans). 25. Chemotherapy and other common drug-induced toxicities of the central nervous system in patients with cancer (J.E. Hammack, T.L. Cascino).
Index.
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