The biochemical basis of neuropharmacology

著者

書誌事項

The biochemical basis of neuropharmacology

Jack R. Cooper, Floyd E. Bloom, Robert H. Roth

Oxford University Press, 2003

8th ed

  • : cloth
  • : pbk

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注記

Includes bibliographical references and index

内容説明・目次

巻冊次

: cloth ISBN 9780195140071

内容説明

This classic text gives a uniquely lucid and lively view of neurotransmitters, their role in nervous system function, and their involvement in the mechanisms of psychiatric drug action. For three decades it has served as an essential guide for students of neuroscience and psychopharmacology, psychiatrists, and neurologists. Both authoritative and very readable, it has been thoroughly updated for each edition. In the eigth edition more space is devoted to clinical examples, subclasses of receptors that provide targets for new drugs, molecular genetics, the major problem of drug delivery to the brain and the growing recognition of nicotinic receptors in the brain and their possible involvement in Alzheimer's and Parkinson's disease. From reviews of the previous edition: "Recommended without reservation to students, physicians and scientists who seek a lucid survey of the biochemical basis of neuronal regulatory systems." New England Journal of Medicine "The best introductory text available for those who want to learn about the application of biochemical approaches to the study of neurotransmitter and drug actions in the nervous system." Brain "This now classic monograph remains a clear and concise guide...(It) should be mandatory reading for all medical students, psychiatry residents, graduate students in neuroscience and pharmacology, and is even useful for undergraduate students." Contemporary Psychiatry.

目次

  • 1. Introduction
  • 2. Cellular Foundations of Neuropharmacology
  • 3. Molecular Foundations of Neuropharmacology
  • 4. Receptors
  • 5. Modulation of Synaptic Transmission
  • 6. Amino Acid Transmitters
  • 7. Acetylcholine
  • 8. Norepinephrine and Epinephrine
  • 9. Dopamine
  • 10. Serotonin (5-Hydroxytryptamine), Histamine, and Adenosine
  • 11. Neuroactive Peptides
  • 12. Cellular Mechanisms in Learning and Memory
  • 13. Treating Neurological and Psychiatric Disorders
巻冊次

: pbk ISBN 9780195140088

内容説明

Aside from the usual updating of material, the major change in this edition is an extensive re-writing of the chapter on memory and learning to emphasize that genes that are involved in behaviour are not immutable but their expression can be modified by transcription factors. Thus, with respect to learning, that old question about which is more important, nature or nuture, genetics or environment, should be answered with the question, which leg is more important for walking, the left or the right?

目次

  • Cellular Foundations of Neuropharmacology
  • Molecular Foundations of Neuropharmacology
  • Receptors
  • Modulation of Synaptic Transmission
  • Amino Acid Transmitters
  • Acetylcholine
  • Norepinephrine and Epinephrine
  • Dopamine
  • Serotonin (50 Hydroxytryptamine), Histamine, and Adenosine
  • Neuroactive Peptides
  • Cellular Mechanisms in Learning and Memory
  • Treating Neurological and Psychiatric Disorders.

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