Goodman & Gilman's the pharmacological basis of therapeutics

著者

• Hardman, Joel G.
• Limbird, Lee E.
• Gilman, Alfred Goodman

書誌事項

Goodman & Gilman's the pharmacological basis of therapeutics

editors, Joel G. Hardman, Lee E. Limbird ; consulting editor, Alfred Goodman Gilman

McGraw-Hill, c2001

10th ed

• International ed.

タイトル別名

The pharmacological basis of therapeutics

注記

Includes bibliographical references and index

内容説明・目次

巻冊次

International ed. ISBN 9780071124324

内容説明

The Tenth Edition also brings the field of pharmacology up-to-date in terms of critical areas such as molecular biology, new drugs, and clinical studies that have contributed to the understanding of therapeutics and their role in the management of disease. Time-tested, yet up-to-the-minute, "G & G" is truly the most current, expert, and easy-to-use drug reference available today.Visit http://www.goodmanandgilman.com for more information.

目次

• Section I: General Principles. Introduction. 1. Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, and Elimination. 2. Pharmacodynamics: Mechanisms of Drug Action and the Relationship Between Drug Concentration and Effect. 3. Principles of Therapeutics. 4. Principles of Toxicology and Treatment of Poisoning. 5. Gene-Based Therapy. Section II: Drugs Acting at Synaptic and Neuroeffector Junctional Sites. 6. Neurotransmission: The Autonomic and Somatic Motor Nervous Systems. 7. Muscarinic Receptor Agonists and Antagonists. 8. Anticholinesterase Agents. 9. Agents Acting at the Neuromuscular Junction and Autonomic Ganglia. 10. Catecholamines, Sympathomimetic Drugs, and Adrenergic Receptor Antagonists. 11. 5-Hydroxtryptamine (Serotonin) Receptor Agonists and Antagonists. Section III: Drugs Acting on the Central Nervous System. 12. Neurotransmission and the Central Nervous System. 13. History and Principles of Anesthesiology. 14. General Anesthetics. 15. Local Anesthetics. 16. Therapeutic Gases. 17. Hypnotics and Sedatives. 18. Ethanol. 19. Drugs and the Treatment of Psychiatric Disorders: Depression and Anxiety. 20. Drugs and the Treatment of Psychiatric Disorders: Psychosis and Mania. 21. Drugs Effective in the Therapy of the Epilepsies. 22. Treatment of the Central Nervous System Degenerative Disorders. 23. Opioid Analgesics and Antagonists. 24. Drug Addiction and Drug Abuse. Section IV: Autacoids
• Drug Therapy of Inflammation. 25. Histamine, Bradykinin, and Their Antagonists. 26. Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor. 27. Analgesic-Antipyretic and Antiinflammatory Agents and Drugs Employed in the Treatment of Gout. 28. Drugs Used in the Treatment of Asthma. Section V: Drugs Affecting Renal and Cardiovascular Function. 29. Diuretics. 30. Vasopressin and Other Agents Affecting the Renal Conservation of Water. 31. Renin and Angiotensin. 32. Drugs Used for the Treatment of Myocardial Ischemia. 33. Antihypertensive Agents and the Drug Therapy of Hypertension. 34. Pharmacological Treatment of Heart Failure. 35. Antiarrhythmic Drugs. 36. Drugs Used in the Treatment of Hyperlipoproteinemias. Section VI: Drugs Affecting Gastrointestinal Function. 37. A. Treatment of Acid-Peptic Diseases. 38. B. Prokinetic and Anti-Emetic Drugs. 39. C. Gastrointestinal Motility & Luminal Flux. Section VII: Chemotherapy of Microbial Diseases. 40. Drugs Used in the Chemotherapy of Protozoal Infections: Malaria. 41. Drugs Used in the Chemotherapy of Protozoal Infections: Trypanosomiasis, Leishmaniasis, Amebiasis, Giardiasis, Trichomoniasis, and Other Protozoal Infections. 42. Drugs Used in the Chemotherapy of Helminthiasis. Section VIII: Chemotherapy of Microbial Diseases. 43. Antimicrobial Agents: General Considerations. 44. Antimicrobial Agents: Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections. 45. Antimicrobial Agents: Penicillins, Cephalosporins, and Other B-Lactam Antibiotics. 46. Antimicrobial Agents: The Aminoglycosides. 47. Antimicrobial Agents: Tetracyclines, Chloramphenicol, Erythromycin, and Miscellaneous Antibacterial Agents. 48. Antimicrobial Agents: Drugs Used in the Chemotherapy of Tuberculosis and Leprosy. 49. Antimicrobial Agents: Antifungal Agents. 50. Antimicrobial Agents: Antiviral Agents. 51. Antimicrobial Agents: Antiretroviral Agents. Section IX: Chemotherapy of Neoplastic Diseases. 52. Antineoplastic Agents. Section X: Drugs Used for Immunomodulation. 53. Immunomodulators: Immunosuppressive Agents and Immunostimulants. Section XI: Drugs Acting on the Blood and the Blood-Forming Organs. 54. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. 55. Antiocagulant, Thrombolytic, and Antiplatelet Drugs. Section XII: Hormones and Hormone Antagonists. 56. Adenohypophyseal Hormones and Their Hypothalamic Releasing Factors. 57. Thyroid and Antithyroid Drugs. 58. Estrogens and Progestins. 59. Androgens. 60. Adrenocorticotropic Hormone
• Adrenocortical Steroids and Their Synthetic Analogs
• Inhibitors of the Synthesis and Actions of Adrenocortical Hormones. 61. Insulin, Oral Hypoglycemic Agents, and the Pharmacology of the Endocrine Pancreas. 62. Agents Affecting Calcification and Bone Turnover: Clacium, Phosphate, Parathyroid Hormone, Vitamin D, Calcitonin, and Other Compounds. Section XIII: The Vitamins. 63. Water-Soluble Vitamins: The Vitamin B Complex and Ascorbic Acid. 64. Fat-Soluble Vitamins: Vitamins A, K, and E. Section XIV: Dermatology. 65. Dermatological Pharmacology. Section XV: Opthalmology. 66. Ocular Pharmacology. Section XVI: Toxicology. 67. Heavy Metals and Heavy-Metal Antagonists. 68. Nonmetallic Environmental Toxicants: Air Pollutants, Solvents, Vapors, and Pesticides. Appendices: I. Principles of Prescription Order Writing and Patient Compliance Instructions. II. Design and Optimization of Dosage Regimens
• Pharmacokinetic Data.

巻冊次

ISBN 9780071354691

内容説明

Completely updated and revisedEvery chapter in the new 10th Edition has been thoroughly revised to reflect the most current research. Approximately one third have been written or revised by new authors and most are reviewed by a clinician and a pharmacist to ensure the highest level of clinical relevance and accuracy. In addition, you'll find:A new introduction by Nobel Prize Laureate, Alfred Goodman Gilman, which provides a fascinating overview of the book and its history plus an insightful look at the future of pharmacologyInformation on more than 150 new drugs released since the last editionMore coverage of antiviral drugsA new chapter on anti-HIV drugsAn updated compilation of the pharmacokinetic features of major drugsThe current status and potential therapeutic value of gene based therapiesCarefully selected and updated bibliographies for each chapterHigh quality two-colour art in every chapterValuable chapter synopses to introduce each chapter, guide you on key points and point out links with other relevant chapters.

目次

• Section I: General Principles. Introduction. 1. Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, and Elimination. 2. Pharmacodynamics: Mechanisms of Drug Action and the Relationship Between Drug Concentration and Effect. 3. Principles of Therapeutics. 4. Principles of Toxicology and Treatment of Poisoning. 5. Gene-Based Therapy. Section II: Drugs Acting at Synaptic and Neuroeffector Junctional Sites. 6. Neurotransmission: The Autonomic and Somatic Motor Nervous Systems. 7. Muscarinic Receptor Agonists and Antagonists. 8. Anticholinesterase Agents. 9. Agents Acting at the Neuromuscular Junction and Autonomic Ganglia. 10. Catecholamines, Sympathomimetic Drugs, and Adrenergic Receptor Antagonists. 11. 5-Hydroxtryptamine (Serotonin) Receptor Agonists and Antagonists. Section III: Drugs Acting on the Central Nervous System. 12. Neurotransmission and the Central Nervous System. 13. History and Principles of Anesthesiology. 14. General Anesthetics. 15. Local Anesthetics. 16. Therapeutic Gases. 17. Hypnotics and Sedatives. 18. Ethanol. 19. Drugs and the Treatment of Psychiatric Disorders: Depression and Anxiety. 20. Drugs and the Treatment of Psychiatric Disorders: Psychosis and Mania. 21. Drugs Effective in the Therapy of the Epilepsies. 22. Treatment of the Central Nervous System Degenerative Disorders. 23. Opioid Analgesics and Antagonists. 24. Drug Addiction and Drug Abuse. Section IV: Autacoids
• Drug Therapy of Inflammation. 25. Histamine, Bradykinin, and Their Antagonists. 26. Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor. 27. Analgesic-Antipyretic and Antiinflammatory Agents and Drugs Employed in the Treatment of Gout. 28. Drugs Used in the Treatment of Asthma. Section V: Drugs Affecting Renal and Cardiovascular Function. 29. Diuretics. 30. Vasopressin and Other Agents Affecting the Renal Conservation of Water. 31. Renin and Angiotensin. 32. Drugs Used for the Treatment of Myocardial Ischemia. 33. Antihypertensive Agents and the Drug Therapy of Hypertension. 34. Pharmacological Treatment of Heart Failure. 35. Antiarrhythmic Drugs. 36. Drugs Used in the Treatment of Hyperlipoproteinemias. Section VI: Drugs Affecting Gastrointestinal Function. 37. A. Treatment of Acid-Peptic Diseases. 38. B. Prokinetic and Anti-Emetic Drugs. 39. C. Gastrointestinal Motility & Luminal Flux. Section VII: Chemotherapy of Microbial Diseases. 40. Drugs Used in the Chemotherapy of Protozoal Infections: Malaria. 41. Drugs Used in the Chemotherapy of Protozoal Infections: Trypanosomiasis, Leishmaniasis, Amebiasis, Giardiasis, Trichomoniasis, and Other Protozoal Infections. 42. Drugs Used in the Chemotherapy of Helminthiasis. Section VIII: Chemotherapy of Microbial Diseases. 43. Antimicrobial Agents: General Considerations. 44. Antimicrobial Agents: Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections. 45. Antimicrobial Agents: Penicillins, Cephalosporins, and Other B-Lactam Antibiotics. 46. Antimicrobial Agents: The Aminoglycosides. 47. Antimicrobial Agents: Tetracyclines, Chloramphenicol, Erythromycin, and Miscellaneous Antibacterial Agents. 48. Antimicrobial Agents: Drugs Used in the Chemotherapy of Tuberculosis and Leprosy. 49. Antimicrobial Agents: Antifungal Agents. 50. Antimicrobial Agents: Antiviral Agents. 51. Antimicrobial Agents: Antiretroviral Agents. Section IX: Chemotherapy of Neoplastic Diseases. 52. Antineoplastic Agents. Section X: Drugs Used for Immunomodulation. 53. Immunomodulators: Immunosuppressive Agents and Immunostimulants. Section XI: Drugs Acting on the Blood and the Blood-Forming Organs. 54. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. 55. Antiocagulant, Thrombolytic, and Antiplatelet Drugs. Section XII: Hormones and Hormone Antagonists. 56. Adenohypophyseal Hormones and Their Hypothalamic Releasing Factors. 57. Thyroid and Antithyroid Drugs. 58. Estrogens and Progestins. 59. Androgens. 60. Adrenocorticotropic Hormone
• Adrenocortical Steroids and Their Synthetic Analogs
• Inhibitors of the Synthesis and Actions of Adrenocortical Hormones. 61. Insulin, Oral Hypoglycemic Agents, and the Pharmacology of the Endocrine Pancreas. 62. Agents Affecting Calcification and Bone Turnover: Clacium, Phosphate, Parathyroid Hormone, Vitamin D, Calcitonin, and Other Compounds. Section XIII: The Vitamins. 63. Water-Soluble Vitamins: The Vitamin B Complex and Ascorbic Acid. 64. Fat-Soluble Vitamins: Vitamins A, K, and E. Section XIV: Dermatology. 65. Dermatological Pharmacology. Section XV: Opthalmology. 66. Ocular Pharmacology. Section XVI: Toxicology. 67. Heavy Metals and Heavy-Metal Antagonists. 68. Nonmetallic Environmental Toxicants: Air Pollutants, Solvents, Vapors, and Pesticides. Appendices: I. Principles of Prescription Order Writing and Patient Compliance Instructions. II. Design and Optimization of Dosage Regimens
• Pharmacokinetic Data.

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詳細情報

• NII書誌ID(NCID): BA53281590
• ISBN:
  • 0071354697
  • 0071124322
• 出版国コード: us
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: New York
• ページ数/冊数: xxvii, 2148 p.
• 大きさ: 26 cm
• 分類:
  • NLM : QV 4
• 件名:
  • LCSH : Pharmacology
  • LCSH : Chemotherapy
  • MESH : Pharmacology
  • MESH : Drug Therapy